Computed tomography diagnosis of tracheobronchopathia osteochondroplastica

White, Barrie; Kong, Andrew; Khoo, Ee Win; Southcott, A M

doi:10.1111/j.1440-1673.2005.01444.x

Cited by 23 publications

(14 citation statements)

References 5 publications

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“…Endobronchial sarcoidosis can also present with nodular lesions of the trachea. Posterior wall involvement of trachea increases the suspicion for polychondritis, sarcoidosis, amyloidosis and papillomatosis (29,30). Diffuse calcification of trachea can also be seen in elderly patients or patients with tuberculosis, chondrosarcoma, Wegener's granulomatosis and fibroma (5,31).All of these conditions should be kept in mind while making the diagnosis of TBPOCP.…”

Section: Differential Diagnosismentioning

confidence: 99%

Tracheobronchopathia osteochondroplastica: a review of the literature

Ulaşlı

Küpeli̇

2014

Clinical Respiratory J

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Background: Tracheobronchopathia osteochondroplastica (TBPOCP) is an uncommon benign condition affecting the lumen of tracheobronchial tree and characterized by abnormal chondrification and ossification. TBPOCP is more frequent than it has been reported, as it can be asymptomatic or present with non-specific respiratory symptoms. Aims: In this article, we provide a review of the English literature on the condition and discuss its clinical features, general principles, diagnostic approaches and current treatment recommendations for TBPOCP.

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Section: Differential Diagnosismentioning

confidence: 99%

Tracheobronchopathia osteochondroplastica: a review of the literature

Ulaşlı

Küpeli̇

2014

Clinical Respiratory J

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“…TO was previously an incidental finding at autopsy due to its usually benign progression and lack of typical symptoms. It is presently increasingly discovered through bronchoscopy and/or chest computed tomography (CT) [5].…”

Section: Introductionmentioning

confidence: 99%

A Clinical Study of Tracheobronchopathia Osteochondroplastica: Findings from a Large Chinese Cohort

Zhu

Huang

et al. 2014

PLoS ONE

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Background and Study AimsTracheobronchopathia osteochondroplastica (TO) is an uncommon disease of the tracheobronchial system that leads to narrowing of the airway lumen from cartilaginous and/or osseous submucosal nodules. The aim of this study is to perform a detailed review of this rare disease in a large cohort of patients with TO proven by fiberoptic bronchoscopy from China.Patients and MethodsRetrospective chart review was performed on 41,600 patients who underwent bronchoscopy in the Department of Respiratory Medicine of Changhai Hospital between January 2005 and December 2012. Cases of TO were identified based on characteristic features during bronchoscopic examination.Results22 cases of bronchoscopic TO were identified. Among whom one-half were male and the mean age was 47.45±10.91 years old. The most frequent symptoms at presentation were chronic cough (n = 14) and increased sputum production (n = 10). Radiographic abnormalities were observed in 3/18 patients and findings on computed tomography consistent with TO such as beaded intraluminal calcifications and/or increased luminal thickenings were observed in 18/22 patients. Patients were classified into the following categories based on the severity of bronchoscopic findings: Stage I (n = 2), Stage II (n = 6) and Stage III (n = 14). The result that bronchoscopic improvement was observed in 2 patients administered with inhaled corticosteroids suggested that resolution of this disease is possible.ConclusionsTO is a benign disease with slow progression, which could be roughly divided into 3 stages on the basis of the characteristic endoscopic features and histopathologic findings. Chronic inflammation was thought to be more important than the other existing plausible hypotheses in the course of TO. Inhaled corticosteroids might have some impact on patients at Stage I/II.

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“…El diagnóstico clínico de TOC no es fácil. Es probable que la incidencia de TOC sea mucho mayor a la conocida y descrita en la bibliografía [11] ya que es una condición que se diagnostica de forma incidental. Los síntomas (cuando se presentan) se superponen con los de otras patologías más frecuentes y la TOC no es tenida en cuenta, la mayor parte de las veces, como hipótesis diagnóstica.…”

Section: Discussionunclassified