Computed Tomography and Magnetic Resonance Imaging of the Thoracic Lymphatic System

Mennini, Maria Luisa; Catalano, Carlo; Monte, Maurizio Del; Fraioli, Francesco

doi:10.1016/j.thorsurg.2011.12.009

Cited by 3 publications

(3 citation statements)

References 37 publications

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“…Hyper-enhancing nodes are suggestive for metastases from hypervascular cancers (i.e., melanoma, renal cell carcinoma) or for Castleman disease [ 78 , 88 ].…”

Section: Differential Diagnosis Of Mediastinal Massesmentioning

confidence: 99%

Tips and Tricks in Thoracic Radiology for Beginners: A Findings-Based Approach

et al. 2023

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This review has the purpose of illustrating schematically and comprehensively the key concepts for the beginner who approaches chest radiology for the first time. The approach to thoracic imaging may be challenging for the beginner due to the wide spectrum of diseases, their overlap, and the complexity of radiological findings. The first step consists of the proper assessment of the basic imaging findings. This review is divided into three main districts (mediastinum, pleura, focal and diffuse diseases of the lung parenchyma): the main findings will be discussed in a clinical scenario. Radiological tips and tricks, and relative clinical background, will be provided to orient the beginner toward the differential diagnoses of the main thoracic diseases.

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“…Hyper-enhancing nodes are suggestive for metastases from hypervascular cancers (i.e., melanoma, renal cell carcinoma) or for Castleman disease [ 78 , 88 ].…”

Section: Differential Diagnosis Of Mediastinal Massesmentioning

confidence: 99%

Tips and Tricks in Thoracic Radiology for Beginners: A Findings-Based Approach

et al. 2023

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“…High-resolution lymphangiography of the peripheral and truncal lymphatics requires the administration of exogenous x-ray or MR contrast agents either directly into the lymphatics via cannulation of a lymphatic vessel (direct lymphangiography; Figure 1, route ii) (9) or indirectly into the lymphatic plexus via intradermal injection (indirect or interstitial lymphangiography; Figure 1, route i) (10). Owing to the difficulties of cannulating small lymphatics in mouse models, direct lymphangiography is not employed in basic science investigations.…”

Section: Imaging Lymphatic Architecture In Humans and Micementioning

confidence: 99%

Emerging lymphatic imaging technologies for mouse and man

2014

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The lymphatic circulatory system has diverse functions in lipid absorption, fluid homeostasis, and immune surveillance and responds dynamically when presented with infection, inflammation, altered hemodynamics, and cancer. Visualization of these dynamic processes in human disease and animal models of disease is key to understanding the contributory role of the lymphatic circulatory system in disease and to devising effective therapeutic strategies. Longitudinal, non-destructive, and repeated imaging is necessary to expand our understanding of disease progression and regression in basic science and clinical investigations. Herein we summarize recent advances in in vivo lymphatic imaging employing magnetic resonance, computed tomography, lymphoscintigraphy, and emerging optical techniques with respect to their contributory roles in both basic science and clinical research investigations.

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“…A wide range of diseases are associated with thoracic lymphadenopathy (1) . Evaluating enlarged lymph nodes is clinically essential for treatment planning and for the pre-0100-3984 © Colégio Brasileiro de Radiologia e Diagnóstico por Imagem http://dx.doi.org/10.1590/0100-3984.2020.0084 diction of the prognosis (2) .…”

Section: Introductionmentioning

confidence: 99%

Diffusion-weighted magnetic resonance imaging for differentiating between benign and malignant thoracic lymph nodes: a meta-analysis

et al. 2021

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Objective: To establish the diagnostic performance of diffusion-weighted magnetic resonance imaging (DWI) in discriminating malignant from non-malignant thoracic lymph nodes. Materials and Methods: This was a meta-analysis involving systematic searches of the MEDLINE, EMBASE, and Web of Science databases up through April 2020. Studies reporting thoracic DWI and lymph node evaluation were included. The pooled sensitivity, specificity, diagnostic odds ratio, positive predictive value, negative predictive value, and area under the receiver operating characteristic curve (AUC) were calculated. Results: We evaluated six studies, involving a collective total of 356 mediastinal lymph nodes in 214 patients. Thoracic DWI had a pooled sensitivity and specificity of 92% (95% confidence interval [95% CI]: 71-98%) and 93% (95% CI: 79-98%), respectively. The positive and negative likelihood ratios were 13.2 (95% CI: 4.0-43.8) and 0.09 (95% CI: 0.02-0.36), respectively. The diagnostic odds ratio was 149 (95% CI: 18-1,243), and the AUC was 0.97 (95% CI: 0.95-0.98). Conclusion: DWI is a reproducible technique and has demonstrated high accuracy for differentiating between malignant and benign states in thoracic lymph nodes.

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Computed Tomography and Magnetic Resonance Imaging of the Thoracic Lymphatic System

Cited by 3 publications

References 37 publications

Tips and Tricks in Thoracic Radiology for Beginners: A Findings-Based Approach

Tips and Tricks in Thoracic Radiology for Beginners: A Findings-Based Approach

Emerging lymphatic imaging technologies for mouse and man

Diffusion-weighted magnetic resonance imaging for differentiating between benign and malignant thoracic lymph nodes: a meta-analysis

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