Computational toolbox for optical tweezers in geometrical optics

Callegari, Agnese; Mijalkov, Mite; Gököz, A. Burak; Volpe, Giovanni

doi:10.1364/josab.32.0000b6

Cited by 9 publications

(5 citation statements)

References 47 publications

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“…Given the generality of the theoretical framework introduced in [ 26 ], our model is well fitted within this context. A freely available software namely Optical Tweezers in Geometrical (OTGO) implements (in MatLab, version R2019a) the theory reported in [ 25 ] in a modular object oriented software [ 28 ]. In the available distribution of OTGO only simple geometrical shapes, such as spheres or ellipsoids, are present, but the modularity of the software makes it easy for researchers to implement new objects describing more complex shapes.…”

Section: Modelmentioning

confidence: 99%

Ray Optics Model for Optical Trapping of Biconcave Red Blood Cells

Tognato

Jones

2022

Micromachines

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Red blood cells (RBCs) or erythrocytes are essential for oxygenating the peripherical tissue in the human body. Impairment of their physical properties may lead to severe diseases. Optical tweezers have in experiments been shown to be a powerful tool for assessing the biochemical and biophysical properties of RBCs. Despite this success there has been little theoretical work investigating of the stability of erythrocytes in optical tweezers. In this paper we report a numerical study of the trapping of RBCs in the healthy, native biconcave disk conformation in optical tweezers using the ray optics approximation. We study trapping using both single- and dual-beam optical tweezers and show that the complex biconcave shape of the RBC is a significant factor in determining the optical forces and torques on the cell, and ultimately the equilibrium configuration of the RBC within the trap. We also numerically demonstrate how the addition of a third or even fourth trapping laser beam can be used to control the cell orientation in the optical trap. The present investigation sheds light on the trapping mechanism of healthy erythrocytes and can be exploited by experimentalist to envisage new experiments.

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Section: Modelmentioning

confidence: 99%

Ray Optics Model for Optical Trapping of Biconcave Red Blood Cells

Tognato

Jones

2022

Micromachines

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“…Rigorous electromagnetic theory [10][11][12] can be used to calculate the torque exerted on a sphere at any range of frequencies or particle sizes. When the particle is much larger than the wavelength of the incident beam, the geometrical optics approximation [13,14] can be employed for the prediction of the radiation torque.…”

Section: Introductionmentioning

confidence: 99%

Direction reversal of the optical spin torque on a Rayleigh absorptive sphere in vector Bessel polarized beams

Yang

Qin

et al. 2016

J. Opt.

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The effect of polarization on the optical spin torque (OST) exerted on an absorptive Rayleigh dielectric sphere by a vector Bessel beam is investigated using the dipole approximation method, with particular emphasis on the polarization of the plane wave component forming the beam. On the basis of the mathematical descriptions for the electric fields, which are derived using the angular spectrum decomposition method in plane waves, analytical formulas of the OST are established. The OSTs are numerically calculated, and the effects of polarization, beam-order, and half-cone angle are discussed in detail. Numerical results show that by choosing an appropriate polarization, order and half-cone angle, the transverse OST will manifest vortex-like behaviors, and the sphere will experience negative axial OSTs, i.e. OST sign reversal. Important applications in particle manipulation, rotation and handling using optical Bessel polarized beams would benefit from the results of the present investigation.

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“…2(d)). For the calculation of the optical forces, as the particle size is significantly larger than the light wavelength, we used a ray optics approach [38] and, for the simulation of the particle motion, we employed Brownian dynamics simulation [39]. The details of the simulated trajectories (Figs.…”

Section: Resultsmentioning

confidence: 99%

Speckle optical tweezers: micromanipulation with random light fields

Volpe¹,

Kurz²,

Callegari³

et al. 2014

Opt. Express

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Current optical manipulation techniques rely on carefully engineered setups and samples. Although similar conditions are routinely met in research laboratories, it is still a challenge to manipulate microparticles when the environment is not well controlled and known a priori, since optical imperfections and scattering limit the applicability of this technique to real-life situations, such as in biomedical or microfluidic applications. Nonetheless, scattering of coherent light by disordered structures gives rise to speckles, random diffraction patterns with welldefined statistical properties. Here, we experimentally demonstrate how speckle fields can become a versatile tool to efficiently perform fundamental optical manipulation tasks such as trapping, guiding and sorting. We anticipate that the simplicity of these "speckle optical tweezers" will greatly broaden the perspectives of optical manipulation for real-life applications.

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Computational toolbox for optical tweezers in geometrical optics

Cited by 9 publications

References 47 publications

Ray Optics Model for Optical Trapping of Biconcave Red Blood Cells

Ray Optics Model for Optical Trapping of Biconcave Red Blood Cells

Direction reversal of the optical spin torque on a Rayleigh absorptive sphere in vector Bessel polarized beams

Speckle optical tweezers: micromanipulation with random light fields

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