Computational study of the blood hemodynamic inside the cerebral double dome aneurysm filling with endovascular coiling

Abstract

The rupture of the aneurysm wall is highly associated with the hemodynamic feature of bloodstream as well as the geometrical feature of the aneurysm. Coiling is known as the most conventional technique for the treatment of intracranial cerebral aneurysms (ICA) in which blood stream is obstructed from entering the sac of the aneurysm. In this study, comprehensive efforts are done to disclose the impacts of the coiling technique on the aneurysm progress and risk of rupture. The computational fluid dynamic method is used for the analysis of the blood hemodynamics in the specific ICA. The impacts of the pulsatile blood stream on the high-risk region are also explained. Wall shear Stress (WSS) and Oscillatory shear index (OSI) factors are also compared in different blood viscosities and coiling conditions. According to our study, the hematocrit test (Hct) effect is evident (25% reduction in maximum WSS) in the two first stages (maximum acceleration and peak systolic). Our findings present that reduction of porosity from 0.89 to 0.79 would decrease maximum WSS by about 8% in both HCT conditions.

Influence of triangular obstacles on droplet breakup dynamics in microfluidic systems

“…A wide range of experimental and numerical studies are employed to investigate fluid flow phenomena in diverse fields, including two phase flow 33 , 34 , porous media, unsteady flow 35 , 36 , aneurysm 37 , 38 , Supersonic flow 39 , 40 , and the manipulation of droplets in microfluidic devices 14 – 23 . According to Link et al 27 , two methods for passively breaking larger droplets into unequal-sized droplets are using an obstacle inside a straight channel and a T-junction with unequal length branches.…”

Impacts of morphology parameters on the risk of rupture in intracranial aneurysms: statistical and computational analyses

“…The size of the aneurysm, including its diameter and volume, has a direct impact on the flow patterns and the magnitude of WSS. Larger aneurysms tend to exhibit lower WSS values, which can result in reduced mechanical stimuli on the vessel wall and potentially contribute to an increased risk of rupture 11 – 13 .…”

Analysis of the effects of stent-induced deformation on the hemodynamics of MCA aneurysms

“…The rupture of an aneurysm can lead to death or debilitation, and endovascular coils are the primary conventional treatment technique used to obstruct aneurysms and reduce the risk of rupture. Previous reports suggest that the quality of coiling plays a crucial role in reducing the risk of aneurysm rupture, particularly in the aneurysm ostium region, which experiences high-velocity impinging blood flow due to poor filling 1 , 2 . If there is a residual neck or unoccupied neck remnant, growth, recanalization, and rupture may occur, making treatment essential 3 – 5 .…”