“…A combination within POD and RB tools is not new, of course, for example, we mention the POD-greedy synergy approaches for unsteady problems [Haasdonk, Ohlberger, 2008 where the time evolution is captured by POD and physical and/or geometrical parameters are managed by greedy techniques. Recent works in cardiovascular modeling and simulations with reduced order methods are devoted to fluid-structure interactions (see , Lassila et al, 2012, Bertagna, Veneziani, 2014), stability of flows and bifurcations (see [Pitton et al, 2017, Pitton, Rozza, 2017 as a references), optimization and control (e.g., see [Manzoni et al, 2012c, Lassila et al, 2013a, Lassila et al, 2013b). Last, but not least, we mention two other reduction techniques: the Proper Generalized Decomposition (PGD, see [Chinesta et al, 2016] as a reference) and the Hierarchical Model Reduction (HIMOD) for flows (see [Baroli et al, 2016]).…”