Computational methods and fast hybrid stochastic simulations for triangulation sensing and identifying principles of cell navigation in the brain
Ulrich Dobramysl,
David Holcman
Abstract:Brownian simulations can be used to generate statistics relevant for studying molecular interactions or trafficking. However, the concurrent simulation of many Brownian trajectories at can become computationally intractable. Replacing detailed Brownian simulations by a rate model was the basis of Gillespie's algorithm, but requires one to disregard spatial information. However, this information is crucial in molecular and cellular biology. Alternatively one can use a hybrid approach, generating Brownian paths … Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.