Computational insights of 1-Guanidinosuccinimide and Benzene-ethanamine, 2,5-difluoro-β- 3,4-trihydroxy-n-methyl with MDM2 as Potential Anticancer Agent
Bulus Bako,
Emmanuel E. Etim,
John P. Shinggu
et al.
Abstract:Cancer remains a significant challenge in healthcare, spurring ongoing exploration for effective therapies. Computational methods, emerging as invaluable tools in drug discovery, have garnered attention for their cost-effectiveness and efficiency. In this study, we investigate the anticancer potential of 1-Guanidinosuccinimide and Benzene-ethanamine, 2,5-difluoro-β, 3,4-trihydroxy-n-methyl, targeting Mouse double minute 2, a critical protein in cancer pathways. Quantum chemical calculations with GAUSSIAN 09 (B… Show more
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