Computational fluid–structure interaction: methods and application to a total cavopulmonary connection

Bazilevs, Yuri; Hsu, Ming‐Chen; Benson, David J.; Sankaran, Sethuraman; Marsden, Alison L.

doi:10.1007/s00466-009-0419-y

Cited by 226 publications

(120 citation statements)

References 47 publications

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“…They determined the wall thickness information when constructing an 'estimated zero-pressure (EZP) arterial geometry' for image-based arterial geometries by trying different ratios of wall thickness to the diameter of the arterial lumen. Other methods proposed include solving the Laplace equation over the arterial volume mesh [62] and over the surface mesh covering the lumen [63]. Since our models are idealized geometries without non-uniformities or complex variations, we used a constant wall thickness for all three layers throughout the vessel.…”

Section: Model Geometrymentioning

confidence: 99%

“…The monolithic (i.e., strongly coupled) techniques, which are the block-iterative, quasi-direct, and direct coupling techniques, are suggested to be more robust, and quasi-direct and direct coupling techniques are especially relevant for FSI analysis with light structures [62,68]. In this study, the approach that the commercial package Ansys offers was used.…”

Section: Numerical Modelingmentioning

confidence: 99%

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Investigation of material modeling in fluid–structure interaction analysis of an idealized three-layered abdominal aorta: aneurysm initiation and fully developed aneurysms

Şimşek

Kwon

2015

J Biol Phys

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Different material models for an idealized three-layered abdominal aorta are compared using computational techniques to study aneurysm initiation and fully developed aneurysms. The computational model includes fluid-structure interaction (FSI) between the blood vessel and the blood. In order to model aneurysm initiation, the medial region was degenerated to mimic the medial loss occurring in the inception of an aneurysm. Various cases are considered in order to understand their effects on the initiation of an abdominal aortic aneurysm. The layers of the blood vessel were modeled using either linear elastic materials or Mooney-Rivlin (otherwise known as hyperelastic) type materials. The degenerated medial region was also modeled in either linear elastic or hyperelastic-type materials and assumed to be in the shape of an arc with a thin width or a circular ring with different widths. The blood viscosity effect was also considered in the initiation mechanism. In addition, dynamic analysis of the blood vessel was performed without interaction with the blood flow by applying time-dependent pressure inside the lumen in a three-layered abdominal aorta. The stresses, strains, and displacements were compared for a healthy aorta, an initiated aneurysm and a fully developed aneurysm. The study shows that the material modeling of the vessel has a sizable effect on aneurysm initiation and fully developed aneurysms. Different material modeling of degeneration regions also affects the stressstrain response of aneurysm initiation. Additionally, the structural analysis without considering FSI (called noFSI) overestimates the peak von Mises stress by 52% at the interfaces of the layers.

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Section: Model Geometrymentioning

confidence: 99%

Section: Numerical Modelingmentioning

confidence: 99%

Investigation of material modeling in fluid–structure interaction analysis of an idealized three-layered abdominal aorta: aneurysm initiation and fully developed aneurysms

Şimşek

Kwon

2015

J Biol Phys

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“…The wall thickness for the remainder of the model is constructed by performing a smooth Laplace operator-based extension of the inlet and outlet thickness data into the domain interior. This vessel wall thickness reconstruction procedure was originally proposed and employed in the simulations of the total cavopulmonary connection in Bazilevs et al (2009b). The resultant wall thickness distribution for the four models is shown in Fig.…”

Section: Materials Parameters and Wall Thicknessmentioning

confidence: 99%

Computational vascular fluid–structure interaction: methodology and application to cerebral aneurysms

Bazilevs

Hsu

Zhang

et al. 2010

Biomech Model Mechanobiol

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235

132

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A computational vascular fluid-structure interaction framework for the simulation of patient-specific cerebral aneurysm configurations is presented. A new approach for the computation of the blood vessel tissue prestress is also described. Simulations of four patient-specific models are carried out, and quantities of hemodynamic interest such as wall shear stress and wall tension are studied to examine the relevance of fluid-structure interaction modeling when compared to the rigid arterial wall assumption. We demonstrate that flexible wall modeling plays an important role in accurate prediction of patient-specific hemodynamics. Discussion of the clinical relevance of our methods and results is provided.

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“…The deformability of the vessels could also been taken into account in the 3D domain: fluid-solid interaction has been shown to influence both pressure and flow in pulmonary arteries, changing not so much the streamlines but more the pressure and wall shear stress, mostly for exercise conditions (Bazilevs et al, 2009). However this requires knowledge of thickness and material properties of the wall, which cannot be easily extracted from the available MRI data.…”

mentioning

confidence: 99%

Group-wise construction of reduced models for understanding and characterization of pulmonary blood flows from medical images

Guibert

McLeod

Caiazzo

et al. 2014

Medical Image Analysis

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Abstract3D computational fluid dynamics (CFD) in patient-specific geometries provides complementary insights to clinical imaging, to better understand how heart disease, and the side effects of treating heart disease, affect and are affected by hemodynamics. This information can be useful in treatment planning for designing artificial devices that are subject to stress and pressure from blood flow. Yet, these simulations remain relatively costly within a clinical context. The aim of this work is to reduce the complexity of patient-specific simulations by combining image analysis, computational fluid dynamics and model order reduction techniques. The proposed method makes use of a reference geometry estimated as an average of the population, within an efficient statistical framework based on the currents representation of shapes. Snapshots of blood flow simulations performed in the reference geometry are used to build a POD (Proper Orthogonal Decomposition) basis, which can then be mapped on new patients to perform reduced order blood flow simulations with patient specific boundary conditions. This approach is applied to a data-set of 17 tetralogy of Fallot patients to simulate blood flow through the pulmonary artery under normal (healthy or synthetic valves with almost no backflow) and pathological (leaky or absent valve with backflow) conditions to better understand the impact of regurgitated blood on pressure and velocity at the outflow tracts.The model reduction approach is further tested by performing patient simulations under exercise and varying degrees of pathophysiological conditions based on reduction of reference solutions (rest and medium backflow conditions respectively).

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Computational fluid–structure interaction: methods and application to a total cavopulmonary connection

Cited by 226 publications

References 47 publications

Investigation of material modeling in fluid–structure interaction analysis of an idealized three-layered abdominal aorta: aneurysm initiation and fully developed aneurysms

Investigation of material modeling in fluid–structure interaction analysis of an idealized three-layered abdominal aorta: aneurysm initiation and fully developed aneurysms

Computational vascular fluid–structure interaction: methodology and application to cerebral aneurysms

Group-wise construction of reduced models for understanding and characterization of pulmonary blood flows from medical images

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