“…Our methods of computational analyses have been previously described. [7][8][9][10][18][19][20] Data for the analyses were acquired by electrocardiogram-gated 320-slice CT imaging. The image data in Digital Imaging and Communications in Medicine format were rendered into three-dimensional patient-specific geometries, including the aorta, coronary arteries, cervical branch arteries, and LVAD outflow graft using a dedicated software (AZE, Tokyo, Japan).…”
Section: Cfd Simulationsmentioning
confidence: 99%
“…5 Computational fluid dynamics (CFD) could help visualize and evaluate the blood flow, flow velocity, wall shear stress, and other fluid dynamic parameters in the three-dimensional aorta. [7][8][9][10] However, previous studies using CFD have only reported blood flow analysis in the ascending aorta without the aortic root because of the complex anatomy of the aortic root and its components such as the aortic valve, coronary arteries, and Valsalva sinus. [11][12][13][14][15] To evaluate the three-dimensional blood flow in the aortic root, three-dimensional patient-specific geometries with accurate anatomy of the aortic root were reproduced using electrocardiogram-gated 320-slice computed tomographic (CT) images.…”
Section: Introductionmentioning
confidence: 99%
“…Although blood flow analysis using vector flow mapping with two‐dimensional echocardiographic images was previously reported, the actual blood flow and shear stress in the three‐dimensional aortic root is unknown . Computational fluid dynamics (CFD) could help visualize and evaluate the blood flow, flow velocity, wall shear stress, and other fluid dynamic parameters in the three‐dimensional aorta . However, previous studies using CFD have only reported blood flow analysis in the ascending aorta without the aortic root because of the complex anatomy of the aortic root and its components such as the aortic valve, coronary arteries, and Valsalva sinus .…”
Mechanical circulatory support with a continuous-flow left ventricular-assist device (LVAD) is a well-established procedure as a bridge to transplantation, and long-term LVAD support has become more important not only as a bridge to transplantation but also as a destination therapy along with improvements in device durability. 1 Aortic insufficiency (AI), while on LVAD, affects 25%-30%
“…Our methods of computational analyses have been previously described. [7][8][9][10][18][19][20] Data for the analyses were acquired by electrocardiogram-gated 320-slice CT imaging. The image data in Digital Imaging and Communications in Medicine format were rendered into three-dimensional patient-specific geometries, including the aorta, coronary arteries, cervical branch arteries, and LVAD outflow graft using a dedicated software (AZE, Tokyo, Japan).…”
Section: Cfd Simulationsmentioning
confidence: 99%
“…5 Computational fluid dynamics (CFD) could help visualize and evaluate the blood flow, flow velocity, wall shear stress, and other fluid dynamic parameters in the three-dimensional aorta. [7][8][9][10] However, previous studies using CFD have only reported blood flow analysis in the ascending aorta without the aortic root because of the complex anatomy of the aortic root and its components such as the aortic valve, coronary arteries, and Valsalva sinus. [11][12][13][14][15] To evaluate the three-dimensional blood flow in the aortic root, three-dimensional patient-specific geometries with accurate anatomy of the aortic root were reproduced using electrocardiogram-gated 320-slice computed tomographic (CT) images.…”
Section: Introductionmentioning
confidence: 99%
“…Although blood flow analysis using vector flow mapping with two‐dimensional echocardiographic images was previously reported, the actual blood flow and shear stress in the three‐dimensional aortic root is unknown . Computational fluid dynamics (CFD) could help visualize and evaluate the blood flow, flow velocity, wall shear stress, and other fluid dynamic parameters in the three‐dimensional aorta . However, previous studies using CFD have only reported blood flow analysis in the ascending aorta without the aortic root because of the complex anatomy of the aortic root and its components such as the aortic valve, coronary arteries, and Valsalva sinus .…”
Mechanical circulatory support with a continuous-flow left ventricular-assist device (LVAD) is a well-established procedure as a bridge to transplantation, and long-term LVAD support has become more important not only as a bridge to transplantation but also as a destination therapy along with improvements in device durability. 1 Aortic insufficiency (AI), while on LVAD, affects 25%-30%
“…Therefore, we performed computerized virtual surgery based on CFD combined with 3D CG. The CFD method was based on our previous validation studies [4,5]. We used the data obtained from thin-slice, early-phase, enhanced multidetector-row CT imaging.…”
A 38-year-old woman presented with exertional dyspnea and chest compression. She had undergone repair of congenital supravalvular aortic stenosis at 8 years of age. Contrast-enhanced computed tomography showed re-stenosis in the ascending aorta, bilateral coronary arterial aneurysm, and a highly thickened left ventricular wall. Release of stenosis was necessary to avoid left ventricular functional deterioration; however, it could cause demand–supply mismatch in coronary flow due to substantial left ventricular hypertrophy. Sufficient statistical evidence was not available in this situation; therefore, computerized virtual surgery based on computational fluid dynamics (CFD) was performed to predict the postoperative hemodynamics. Consequently, root replacement with in situ Carrel patch coronary reconstruction was considered a better option than coronary artery graft bypass in the left-side coronary flow supply. The patient underwent root replacement with in situ Carrel patch coronary reconstruction as planned based on CFD without any complication and was discharged 15 days postoperatively.
“…Their report consequently confirmed that the incidence rate of right-hemisphere stroke was significantly lower in the right axillary artery cannulation group. Numata and colleagues 4 reported that the right subclavian artery cannulation was cerebroprotective with the use of computational fluid dynamics simulation. They showed that a retrograde flow of the brachiocephalic artery and an antegrade flow of the right common carotid artery were produced from the blood streamline from the right subclavian artery throughout the cardiac cycle.…”
The right axillary artery showed positive results in open aortic arch repair. However, this cannulation is only one of several options, and not a final solution, to completely prevent stroke.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.