Computational Fluid Dynamics and Digital Particle Image Velocimetry Study of the Flow Through an Optimized Micro‐axial Blood Pump

Triep, Michael; Brücker, Christoph; Schröder, Wolfgang; Sieß, Thorsten

doi:10.1111/j.1525-1594.2006.00230.x

Cited by 28 publications

(30 citation statements)

References 4 publications

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“…The implementations of these CFD packages are either based on the finite volume23 method or finite element method. Fluent 36, 37, 38, 39, 40, 41 and CFX 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 11, 57, 58, 59, both available from ANSYS, Inc. (Canonsburg, PA) and STAR-CD from CD-Adapco 60, 61 (Melville, New York) are the CFD software packages used most often for analysis and modelling of blood flow in VADs. In addition, AcuSolve from ACUSIM Software 62 (Mountain View, CA) and Adina from Adina R&D (Watertown, MA) are also used.…”

Section: Computational Techniquesmentioning

confidence: 99%

“…The flow in the Impella pump was simulated using a low-Reynolds number k-ε model 61. Simulated axial velocity profiles at many axial locations, and at 0 and 90° circumferential locations, were compared with profiles measured using DPIV.…”

Section: Turbulencementioning

confidence: 99%

“…The longer tips were found to increase the pressure head by around 50 %. In the Impella axial flow pump, Triep et al 61 investigated the effect of the length of the axial tip on the pump’s efficiency. Pumps with magnetically levitated impellers always have a narrow gap which separates the impeller from the pump housing.…”

Section: Design Optimizationmentioning

confidence: 99%

“…The different size, speeds, flow rates and working fluid mean that validation studies should be performed specifically for blood pumps. Validation is usually performed in vitro and most commonly uses the noninvasive optical techniques of flow visualization 74, 36, 187, 100, for qualitative information, and particle image velocimetry 43, 109, 46, 111, 59, 61, 62 or laser Doppler anemometry 188, 100 for quantitative measurements. Another noninvasive technique which can be used to measure the wall shear stress is oil drop streaking 110, 187.…”

Section: Validationmentioning

confidence: 99%

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The use of computational fluid dynamics in the development of ventricular assist devices

Fraser

Taşkın

Griffith

et al. 2011

Medical Engineering & Physics

228

236

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Progress in the field of prosthetic cardiovascular devices has significantly contributed to the rapid advancements in cardiac therapy during the last four decades. The concept of mechanical circulatory assistance was established with the first successful clinical use of heart-lung machines for cardiopulmonary bypass. Since then a variety of devices have been developed to replace or assist diseased components of the cardiovascular system. Ventricular assist devices (VADs) are basically mechanical pumps designed to augment or replace the function of one or more chambers of the failing heart.Computational Fluid Dynamics (CFD) is an attractive tool in the development process of VADs, allowing numerous different designs to be characterized for their functional performance virtually, for a wide range of operating conditions, without the physical device being fabricated. However, VADs operate in a flow regime which is traditionally difficult to simulate; the transitional region at the boundary of laminar and turbulent flow. Hence different methods have been used and the best approach is debatable. In addition to these fundamental fluid dynamic issues, blood consists of biological cells. Device-induced biological complications are a serious consequence of VAD use. The complications include blood damage (haemolysis, blood cell activation), thrombosis and emboli. Patients are required to take anticoagulation medication constantly which may cause bleeding. Despite many efforts blood damage models have still not been implemented satisfactorily into numerical analysis of VADs, which severely undermines the full potential of CFD. This paper reviews the current state of the art CFD for analysis of blood pumps, including a practical critical review of the studies to date, which should help device designers choose the most appropriate methods; a summary of blood damage models and the difficulties in implementing them into CFD; and current gaps in knowledge and areas for future work.

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Section: Computational Techniquesmentioning

confidence: 99%

Section: Turbulencementioning

confidence: 99%

Section: Design Optimizationmentioning

confidence: 99%

Section: Validationmentioning

confidence: 99%

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The use of computational fluid dynamics in the development of ventricular assist devices

Fraser

Taşkın

Griffith

et al. 2011

Medical Engineering & Physics

228

236

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“…13.11). These models have been recently validated by how much the velocity distributions calculated by CFD analysis and those actually measured coincide (Triep et al 2006), although other problems with the accuracy of the velocity measurement arise. Furthermore, validation of the pressure distribution (Burgreen et al 2001), stream path (Apel et al 2001a), and turbulence component is required.…”

Section: Solutionmentioning

confidence: 97%

Vascular Engineering of Circulatory Assist Devices

Nishida

2016

Vascular Engineering

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Heart failure is a condition in which the heart cannot pump sufficiently because its contractile force has deteriorated. Patients with heart failure can sometimes undergo heart transplantation, but in number these patients comprise less than 10 % of patients actually requiring heart transplantation. Thus, mechanical circulatory assistance plays an important role in substituting for heart transplantation wherein the pump function of the heart is assisted by an artificial blood pump called a ventricular assist device. On the other hand, cardiopulmonary bypass is a form of extracorporeal circulation that temporarily takes over the function of the heart and lungs to maintain the circulation of blood and the oxygen content of the body during surgery for heart failure and aneurysms of the thoracic aorta. This chapter describes the vascular engineering of circulatory assist devices. Particular emphasis is placed on recent progress in ventricular assist devices and cardiopulmonary bypass pumps. These important medical devices assist with human circulation at either the chronic or the acute phase. Because these devices are derived from an industrial pump, a great many studies have been conducted not only from the medical perspective but also from industrial and engineering perspectives. In this chapter, current ventricular assist devices and cardiopulmonary bypass pumps, their specifications, their classifications, and methods for their design and evaluating are presented, including flow analysis inside the pump to optimize the geometry.

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Computational Fluid Dynamics for Mechanical Circulatory Support Device Development

Graefe¹,

Pauli

2020

Mechanical Support for Heart Failure

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Computational Fluid Dynamics and Digital Particle Image Velocimetry Study of the Flow Through an Optimized Micro‐axial Blood Pump

Cited by 28 publications

References 4 publications

The use of computational fluid dynamics in the development of ventricular assist devices

The use of computational fluid dynamics in the development of ventricular assist devices

Vascular Engineering of Circulatory Assist Devices

Computational Fluid Dynamics for Mechanical Circulatory Support Device Development

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