Computational Exploration of gp63: Unlocking Potential Inhibitors for Leishmaniasis
Divya Vemula,
Perka Jayasurya,
Vasundhra Bhandari
Abstract:Leishmaniasis is an infection caused by protozoa of the genus Leishmania, which belongs to a neglected group of diseases. Limited treatment options and emerging drug resistance has contributed towards morbidity and mortality due to leishmaniasis. Therefore, exploring new therapeutic targets responsible for the pathogen's virulence is a priority to combat the disease. One of the contributing molecular factors to Leishmania virulence and pathogenesis is the metalloprotease glycoprotein 63 (gp63), also known as l… Show more
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