Compression stockings as an effective treatment for erythema nodosum: Case series

Abstract

Erythema nodosum (EN) is a septal panniculitis that is characterized clinically by tender, erythematous, subcutaneous nodules that are predominately localized on the pretibial lower legs. EN affects women more than men and can be idiopathic or secondary to another disease process such as infection or an immune response. Treatment options for erythema nodosum are suboptimal and often involve significant side effects or require a change in lifestyle. We investigated the effects of moderate 20 mmHg to 30 mmHg compression stockings as an alternative treatment method in two female patients with recurrent erythema nodosum. In both cases, the patients wore the compression stockings daily. At the follow-up visit, the EN lesions were no longer tender to the touch, and postinflammatory hyperpigmentation changes had started. Both patients had a lasting clinical resolution.

Highly suspected valsartan-induced chronic erythema nodosum migrans in a patient with hypertension: a case report

“…Approximately 50% of EN cases are thought to be idiopathic with no cause found. 9 – 10 ENM is a rare variant and special type of EN, and was first described by Bafverstedt in 1954. 11 There have been few studies on ENM, and no case induced by valsartan has been reported.…”

Kompressionstherapie bei entzündlichen Dermatosen der Beine

“…Bei 52 % der Patienten heilte die Wunde vollständig ab; insgesamt 71 % der Patienten konnten ein Selbstmanagement durchführen [27]. Es finden sich weitere Fallberichte zu entzündlichen Dermatosen der Beine bei den Diagnosen Erythema induratum [28], Erythema nodosum [29], Perifolliculitis capitis abscedens et suffodiens [30], Purpura pigmentosa progressiva [31], ulzerierende kutane Sarkoidose [32] und ulzerierende Morphea [33], die von einer Kompressionstherapie profitiert haben.…”

Compression therapy in dermatology

“…11,25 It therefore has a firm place in the hitherto otherwise poorly standardized treatment approaches. 26 Casuistic descriptions are also available for erythema induratum, 27 erythema nodosum, 28 lichen ruber (verrucosus), 25 perifolliculitis capitis abscedens et suffodiens, 29 progressive pigmented purpura, 30 or scleroderma circumscripta. 31 Especially due to the frequently challenging pain symptoms, compression therapy in inflammatory dermatoses can be initiated with low resting pressure values of about 20 mmHg.…”