Compressed glassy carbon: An ultrastrong and elastic interpenetrating graphene network

Hu, Meng; Zhao, Zhisheng; Strobel, Timothy A.; Hu, Wentao; Yu, Dongli; Sun, Hao; Liu, Lingyu; He, Jingliang; Ma, Mengdong; Kono, Yoshio; Shu, Jinfu; Mao, Ho‐kwang; Fei, Yingwei; Shen, Guoyin; Wang, Yanbin; Juhl, Stephen J.; Huang, Jianyu; Liu, Zhongyuan; Xu, Bin; Tian, Yongjun

doi:10.1126/sciadv.1603213

Cited by 122 publications

(81 citation statements)

References 33 publications

(47 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[25][26][27] The model was then allowed to equilibrate using the computer program YASARA for~90ns, as previously described. 28,29 Individual mutations were introduced to the model by the "swap" command in YASARA, and the resulting models were allowed to equilibrate for~100ns.…”

Section: Modeling Of Smybp-c/myosin Interactionmentioning

confidence: 99%

Novel mutations in MYBPC1 are associated with myogenic tremor and mild myopathy

Stavusis

Lāce

Schäfer³

et al. 2019

Annals of Neurology

View full text Add to dashboard Cite

Objective: To define a distinct, dominantly inherited, mild skeletal myopathy associated with prominent and consistent tremor in two unrelated, three-generation families. Methods: Clinical evaluations as well as exome and panel sequencing analyses were performed in affected and nonaffected members of two families to identify genetic variants segregating with the phenotype. Histological assessment of a muscle biopsy specimen was performed in 1 patient, and quantitative tremor analysis was carried out in 2 patients. Molecular modeling studies and biochemical assays were performed for both mutations. Results: Two novel missense mutations in MYBPC1 (p.E248K in family 1 and p.Y247H in family 2) were identified and shown to segregate perfectly with the myopathy/tremor phenotype in the respective families. MYBPC1 encodes slow myosin binding protein-C (sMyBP-C), a modular sarcomeric protein playing structural and regulatory roles through its dynamic interaction with actin and myosin filaments. The Y247H and E248K mutations are located in the NH 2 -terminal M-motif of sMyBP-C. Both mutations result in markedly increased binding of the NH 2 terminus to myosin, possibly interfering with normal cross-bridge cycling as the first muscle-based step in tremor genesis. The clinical tremor features observed in all mutation carriers, together with the tremor physiology studies performed in family 2, suggest amplification by an additional central loop modulating the clinical tremor phenomenology. Interpretation: Here, we link two novel missense mutations in MYBPC1 with a dominant, mild skeletal myopathy invariably associated with a distinctive tremor. The molecular, genetic, and clinical studies are consistent with a unique sarcomeric origin of the tremor, which we classify as "myogenic tremor."Circular dichroism experiments were conducted in a 1-mm pathlength cuvette with wild-type and mutant His-tagged proteins of 15 to 17μM in 20mM phosphate buffer (pH 7.5) and 50mM NaCl. Samples were measured in triplicate at temperatures from 20 C to 90 C in 10 C intervals on a Jasco J-810 spectrophotometer. 132 Volume 86, No. 1

show abstract

Section: Modeling Of Smybp-c/myosin Interactionmentioning

confidence: 99%

Novel mutations in MYBPC1 are associated with myogenic tremor and mild myopathy

Stavusis

Lāce

Schäfer³

et al. 2019

Annals of Neurology

View full text Add to dashboard Cite

show abstract

“…Thus, it might be possible to synthesize some of the newly predicted superhard phases under pressure by an appropriate choice of the carbon allotrope starting material and the synthesis route. Metastable carbon phases have been previously synthesized by compressing glassy carbon [49,50] or onion carbon [51,52], for instance. To study this further, we computed the pressures above which the newly predicted superhard phases become more stable than graphite.…”

Section: Applications To Carbonmentioning

confidence: 99%

Predicting superhard materials via a machine learning informed evolutionary structure search

et al. 2019

View full text Add to dashboard Cite

Good agreement was found between experimental Vickers hardnesses, Hv, of a wide range of materials and those calculated by three macroscopic hardness models that employ the shear and/or bulk moduli obtained from: (i) first principles via AFLOW-AEL (AFLOW Automatic Elastic Library), and (ii) a machine learning (ML) model trained on materials within the AFLOW repository. Because H ML v values can be quickly estimated, they can be used in conjunction with an evolutionary search to predict stable, superhard materials. This methodology is implemented in the XTALOPT evolutionary algorithm. Each crystal is minimized to the nearest local minimum, and its Vickers hardness is computed via a linear relationship with the shear modulus discovered by Teter. Both the energy/enthalpy and H ML v, Teter are employed to determine a structure's fitness. This implementation is applied towards the carbon system, and 43 new superhard phases are found. A topological analysis reveals that phases estimated to be slightly harder than diamond contain a substantial fraction of diamond and/or lonsdaleite. arXiv:1906.05886v1 [cond-mat.mtrl-sci]

show abstract

“…The sp 3 carbon bonds are easily formed between the interlayers. They can also be formed at curved surfaces of graphene sheets fragments . The fullerene‐like carbon network would consist of local buckling or cross‐linkage of graphene sheets through sp 3 carbon bonds.…”

Section: The Data Of the Deconvoluted Raman Spectra Of The Flc:h Filmsmentioning

confidence: 99%

Super‐Elasticity and Ultralow Friction of Hydrogenated Fullerene‐Like Carbon Films: Associated with the Size of Graphene Sheets

Cao

Zhao

Liu

et al. 2018

Adv Materials Inter

View full text Add to dashboard Cite

such as high-hardness/strength, excellent elasticity, and high compressibility. [1][2][3][4] Carbon nitride films, [5] pure carbon films, [6] and hydrogenated carbon films [7] containing these fullerene-like structures have been proved to possess excellent elastic recovery rate (85%, 80%, and 85%, respectively) and high hardness values (60, 53, and 19 GPa, respectively). In particular, hydrogenated fullerene-like carbon (FLC:H) films can also exhibit ultralow friction behaviors, which are desirable to minimize mechanical dissipation. These properties are essential for the application of these materials as protective coatings to engineering components. But the exact relationship between these properties and the fullerene-like structures is still unclear. The nanostructure of graphene sheets and the number of cross-linking sites between them may be two main structural factors determining these properties. Exploring the structureproperties relationship is crucial to effectively tailor these properties for potentially more applications. Some relevant studies have demonstrated that fullerene-like spheroids (FLS) encased in disordered graphene layers [4] and aligned carbon nanotube films [8] can display a lot of mechanical characteristics similar to those of architectured materials. Controlling the size, concentration, and connectivity of FLS or manipulating buckled morphologies of nanotube can tailor their mechanical properties. Thus, it is expected that FLC films may yield exceptional and tunable mechanical properties by controlling the nanostructure of graphene sheets. However, there are very few experimental reports on these issues, because designing and controlling the nanostructure of graphene sheets in FLC films remains a technical challenge.Recently a number of methods, such as ion beam-assisted deposition, molecular beam epitaxy, and plasma enhanced chemical vapor deposition (PECVD) have been developed for manufacturing high quality graphene-like materials. [9][10][11] It has been demonstrated that low-energy argon ions bombardment in these deposition systems is beneficial for the formation of graphene network. [12][13][14] Molecular dynamics simulations experiments also showed that low-energy (10-25 eV) argon ions bombardment could result in an increase in the number of graphitic rings and further enhance the graphene network growth. [13,15] The formation of curved graphene sheets (CGS) in magnetron-sputtered CN x films was mainly attributed to Hydrogenated fullerene-like carbon (FLC:H) films would be a widely used material with a unique combination of properties including high-hardness/ strength, excellent elasticity, and ultralow friction. The nanostructure of graphene sheets and the number of cross-linking sites between them may be two main structural factors determining these properties. Exploring the structure-properties relationship is crucial to effectively tailor these properties for potentially more applications. In this study it is demonstrated that FLC:H films can yield exceptional and tunable mec...

show abstract

Compressed glassy carbon: An ultrastrong and elastic interpenetrating graphene network

Abstract: The compression of glassy carbon forms a series of lightweight, ultrastrong, hard, elastic, and conductive carbons.

Cited by 122 publications

References 33 publications

Novel mutations in MYBPC1 are associated with myogenic tremor and mild myopathy

Novel mutations in MYBPC1 are associated with myogenic tremor and mild myopathy

Predicting superhard materials via a machine learning informed evolutionary structure search

Super‐Elasticity and Ultralow Friction of Hydrogenated Fullerene‐Like Carbon Films: Associated with the Size of Graphene Sheets

Contact Info

Product

Resources

About