Comprehensive treatment of endometrial hyperplasia for women of reproductive age with metabolic syndrome

Shcherbyna, Mykola; Tkachova, O.; Shcherbyna, I.M.; Lypko, O.P.; Kapustnyk, Nataliia V

doi:10.15574/hw.2016.110.124

Cited by 1 publication

(3 citation statements)

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“…У випадку ЗДА плацентарна недостатність має місце у 25%, слабкість родової діяльностіу 42%, гіпотонічна кровотеча в післяродовому періодіу 47%, гнійно-септичні втратиу 12%, що сприяє збільшенню ризику перинатальної загибелі плода [10]. Запальні процеси у структурних компонентах посліду можуть обумовлювати ряд ускладнень: плацентарну недостатність, передчасне відходження навколоплідних вод, невиношування вагітності, внутрішньоутробне інфікування та мертвонародження [11].…”

Section: вступunclassified

“…Вагітні із захворюваннями сечостатевої системи у матері (ерозія шийки матки, ендоцервіцит, кольпіт, вульвовагініт, кіста яєчників, внутрішньоматкові зрощення, сечова інфекція у вигляді уретриту, циститу, пієлонефриту та ін.) безперечно належать до групи підвищеного ризику стосовно ускладнень перебігу вагітності та пологів [11].…”

Section: матеріали та методиunclassified

“…У 5 (19,2%) випадках спостерігали фунікуліт, у 4 (15,4%) -інтервелізит. У ряді досліджень відзначається, що запальні зміни плаценти є початковими стадіями внутрішньоутробної інфекції плоду, що може призвести до його загибелі як унаслідок інфікування, так і розвитку плацентарної недостатності та ускладнень з боку матері [11,27].…”

Section: матеріали та методиunclassified

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An analysis of the pathological states of pregnant women in ante-intranatal fetal death in kharkov during 2016-2019

Sherstiuk¹,

Zats²,

Naumova³

et al. 2021

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Background. In Ukraine among perinatal losses, a high proportion of stillbirth remains, the level of which depends on many factors, including the presence of somatic and genital pathology in a woman, pathological conditions during pregnancy, including eclampsia (PE), iron deficiency anemia of pregnant women (IDA), chorioamnionitis (CA). These conditions can be combined with each other, which increases the risk of fetal death during pregnancy or childbirth. Objective. To conduct a somatic and gynecological diseases, complications of pregnancy in pregnant women with preeclampsia (PE), iron deficiency anemia (IDA) and chorioamnionitis (CA), whose pregnancy ended in ante-intrapartum fetal death at 30-40 weeks of gestation. Methods. We investigated 58 cases of stillbirth at 30-40 weeks of gestation from pregnant women with PE (n = 16), IDA (n = 16), CA (n = 26) on the basis of the Communal non-profit enterprise "City Perinatal Center "Kharkov. The clinical data of the mothers, the protocols of the pathological examination of the placenta were studied. Results. Based on the study, it was found that in women whose pregnancy was complicated by PE and IDA, the most frequent types of somatic pathology were hypertensive disorders (32% and 12.5%, respectively) and chronic diseases of the digestive system. (25% and 12.5%, respectively), among gynecological diseases, uterine leiomyoma and endocervicosis were more common, among complications of pregnancy and childbirth - premature birth (50% each, respectively) pathology of the placenta (50% and 68.8%, respectively) and disorders of the content amniotic fluid (31.3% and 18.8%, respectively).The extragenital pathology in pregnant women with CA was presented with the infectious diseases (30.7%), an acute respiratory viral infections (19.2%), the cardiovascular pathology (11.5%), and the chronic inflammatory diseases of various localization (7.6%). The most frequency gynecological pathology were inflammatory genital diseases (23.21%). The pregnancy and labor were often complicated with the placental pathology (50%), premature birth (38.5%), preeclampsia (19.2%), and anemia (19.2%). During pregnancy, placental dysfunction diagnosed only in 31.3% of cases with PE, 25% with IDA and 3.8% with CA, but in pathological examination, morphological signs of placental insufficiency recorded in almost every case of all groups. Conclusion. In pregnancy, aggravated by PE, IDA or CA, the presence of extragenital pathology, gynecological diseases, and other complications of pregnancy were additional factors that increased the severity of placental insufficiency and fetal hypoxia, which was the cause of its death. Timely diagnosis of placental dysfunction and the implementation of therapeutic measures aimed at reducing the associated negative impact on the fetus can help reduce perinatal mortality.

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Section: вступunclassified

Section: матеріали та методиunclassified