Comprehensive transcriptomic and metabolomic analysis of porcine intestinal epithelial cells after PDCoV infection
Guangzheng Wang,
Yanan Cao,
Chao Xu
et al.
Abstract:IntroductionPorcine deltacoronavirus (PDCoV), an emerging swine enteropathogenic coronavirus with worldwide distribution, mainly infects newborn piglets with severe diarrhea, vomiting, dehydration, and even death, causing huge economic losses to the pig industry. However, the underlying pathogenic mechanisms of PDCoV infection and the effects of PDCoV infection on host transcripts and metabolites remain incompletely understood.MethodsThis study investigated a combined transcriptomic and metabolomic analysis of… Show more
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