Comprehensive transcriptomic analysis identifies SLC25A4 as a key predictor of prognosis in osteosarcoma
Ying Zhang,
Yinghui Wang,
Wenyan Zhang
et al.
Abstract:BackgroundOsteosarcoma (OS) is highly malignant and prone to local infiltration and distant metastasis. Due to the poor outcomes of OS patients, the study aimed to identify differentially expressed genes (DEGs) in OS and explore their role in the carcinogenesis and progression of OS.MethodsRNA sequencing was performed to identify DEGs in OS. The functions of the DEGs in OS were investigated using bioinformatics analysis, and DEG expression was verified using RT-qPCR and Western blotting. The role of SLC25A4 wa… Show more
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