Achieving sustainability is the ultimate goal-oriented challenge. Control science can be applied to all goal-oriented tasks. Accordingly, utilizing control science, we have been progressing in research on sustainability and sustainable design. Here this chapter illustrates the methodology for designing sustainable structures with two examples. In this context, “structures” include various city components, such as buildings, roads, and parks, as well as the whole city. First, this chapter illustrates the control system for promoting sustainable structure design. Next, it shows the process of producing and revising sustainable structure design guidelines. Based on this process, Section 4 demonstrates how to produce and revise sustainable housing design guidelines, with the completed guidelines’ extracts. Moreover, Section 5 outlines a way of producing sustainable urban design guidelines. Designing the whole city needs extensive spatial planning; therefore, the guidelines consist of three parts: (1) development allowable areas, (2) spatial relationships among city components, (3) principles of designing city components. This methodology’s characteristics include visualization of the whole picture for promoting sustainable design, user-friendliness, comprehensiveness, and adaptability to different and changing situations.