Comprehensive Screening and Evaluation of Anti-gout Activity of Plantago asiatica L. through Integrated In vivo and In vitro Methodologies
Hong-Xue Gao,
Zhi-Qiang Liu,
Zong Hou
et al.
Abstract:Objective:
This study aimed to elucidate the active components and mechanisms of Plantago asiatica L. (PAL) in the treatment of gout.
Materials and Methods:
Based on its polarity, PAL was partitioned into three parts, P1, P2, and P3, through gradient elution using AB-8 macroporous resin columns. The primary constituents of these fractions include iridoids, phenylethanoid glucosides, and flavonoids. Subsequently, a comprehensive in vitro and in vivo scre… Show more
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