Comprehensive review of Pluronic® polymers of different shapes with prominent applications in photodynamic therapy

Kumar, Saran S.; Harikrishnan, K.K.; Urmila, S.P.; Gauri, V.; Saritha, Appukuttan; Gangopadhyay, Moumita

doi:10.1016/j.eurpolymj.2023.112534

Cited by 2 publications

(2 citation statements)

References 142 publications

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“…The SEM images clearly show the existence of aggregated rod-like particles tightly packed in the sample. The observed aggregation of these rod-like structures is likely the result of interactions and integration of reactants with various surfactant aggregates 43 . Furthermore, using Zetasizer measurements, we found that the particle size ranges from 213 to 452 nm, providing valuable insights into the size distribution of the encapsulated nanoparticles.…”

Section: Resultsmentioning

confidence: 98%

Synthesis, characterization of poly l(+) lactic acid and its application in sustained release of isosorbide dinitrate

Kenawy,

Abd El.Hay,

Saad

et al. 2024

Sci Rep

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Poly l(+) lactic acid (PLLA) has become crucial in the biomedical industry for various uses. The direct polycondensation method was used to prepare Poly l(+) Lactic Acid (PLLA). Different catalysts, including metal oxides and metal halides, were used to test the polymerization technique. The effect of the amount of catalysts and the type of coupling agent were investigated. The effect of reaction time and polymerization solvents was also studied. PLLA was loaded with isosorbide dinitrate utilizing the solvent evaporation process. The synthesized polymer-drug system was evaluated by different means such as FT-IR, TGA, DSC, XRD, entrapment efficiency (E.E), drug loading (D.L), particle size analysis, and zeta potential determination. Studies on in-vitro release using UV light at 227 nm at various pH levels were conducted, and the kinetics of release and cytotoxicity using the sulforhodamine B (SRB) assay on human skin fibroblast cells were examined.

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Section: Resultsmentioning

confidence: 98%

Synthesis, characterization of poly l(+) lactic acid and its application in sustained release of isosorbide dinitrate

Kenawy,

Abd El.Hay,

Saad

et al. 2024

Sci Rep

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“…These copolymers are known for their excellent biocompatibility and are used for making coatings, drug delivery devices, and thickeners, among many other applications. Their distinct structure, made up of ethylene oxide and propylene oxide blocks, allows for a wide range of functions, making them extremely valuable in numerous technological areas, including cosmetics, pharmaceuticals, food science, catalysis, and materials science [1][2][3][4][5][6][7]. The multifaceted utility of Pluronic copolymers derives from their distinctive surfactant properties, which enable them to modify surface interactions and stabilize different types of systems, including emulsion droplets, colloidal particles, capsules, or liposomes [8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Ionic Strength Effect in the Equilibrium and Rheological Behavior of an Amphiphilic Triblock Copolymer at the Air/Solution Interface

Carbone,

Guzmán,

Maldonado-Valderrama

et al. 2024

Colloids and Interfaces

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This study investigates the effect of an inert salt (NaCl) on the equilibrium interfacial tension and dilatational modulus of Pluronic F-68 copolymer, a triblock copolymer consisting of two terminal blocks of poly(ethylene oxide) and a less hydrophilic central block of poly(propylene oxide). Interfacial tension measurements were carried out using a surface force balance and a drop shape tensiometer, while rheological measurements were carried out in two different frequency ranges. This involved the use of the oscillatory barrier/droplet method and electrocapillary wave measurements, complemented by an appropriate theoretical framework. This work aimed to elucidate the influence of NaCl on the interfacial behavior of Gibbs monolayers of Pluronic F-68. In addition, this study highlights some of the technical and theoretical limitations associated with obtaining reliable dilatational rheological data at high frequencies (<1 kHz) using electrocapillary wave measurements. The results provide valuable insights into the interplay between salt presence and interfacial properties of Pluronic F-68 and highlight the challenges of obtaining accurate dilatational rheological data under specific measurement conditions.

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Comprehensive review of Pluronic® polymers of different shapes with prominent applications in photodynamic therapy

Cited by 2 publications

References 142 publications

Synthesis, characterization of poly l(+) lactic acid and its application in sustained release of isosorbide dinitrate

Synthesis, characterization of poly l(+) lactic acid and its application in sustained release of isosorbide dinitrate

Ionic Strength Effect in the Equilibrium and Rheological Behavior of an Amphiphilic Triblock Copolymer at the Air/Solution Interface

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