Comprehensive phytochemical analysis of lingonberry (<i>Vaccinium vitis-idaea</i> L.) from different regions of China and their potential antioxidant and antiproliferative activities

Xu, Jian; Yang, Han; Nie, Chengdong; Wang, Tao; Qin, Xiangyu; Yang, Jie; Chang, Yuanhang; Nie, Siming; Fu, Yujie

doi:10.1039/d3ra05698h

Cited by 1 publication

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References 41 publications

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“…These compounds exhibit a myriad of health-promoting attributes, such as astringent, antitussive, diuretic, neuroprotective, antioxidant, and anti-inflammatory activities. Their potential roles in inhibiting cancer cell proliferation further underscore their therapeutic potential [5].…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Activity, Formulation, Optimization and Characterization of an Oil-in-Water Nanoemulsion Loaded with Lingonberry (Vaccinium vitis-idaea L.) Leaves Polyphenol Extract

Wang,

Cheng,

Wang

et al. 2023

Foods

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The active ingredients in lingonberry leaves and their beneficial properties to the human body have been well confirmed. In order to improve the stability and antioxidant activity of the active ingredients in lingonberry leaves, the response surface optimization method was used to prepare an oil-in-water nanoemulsion of polyphenol extract from lingonberry leaves. The active components in the extract were analyzed by ultra-performance liquid chromatography with triple quadrupole mass spectrometry (UPLC-TQ-MS), and bioactive compounds such as apigenin, sorbitol, and hesperidin were mainly found. Nanoemulsion droplets of 120 nm in diameter were prepared using ultrasonic emulsification. The optimal nanoemulsion formulation was determined through rigorous testing, and it was determined to be 10% (w/w) lingonberry extract and 20% (w/w) medium chain triglyceride (MCT). Additionally, a surfactant mixture was used, which combined soy protein isolate (SPI) and whey protein isolate (WPI) at 4% (w/w). The preparation method utilized ultrasonic emulsification, applying an ultrasonic power of 360 W for a duration of 300 s. The antioxidant activity (DPPH inhibition rate, ABTS inhibition rate and total reducing power) of the lingonberry nanoemulsion was significantly higher than that of the lingonberry polyphenol (LBP) extract. The nanoemulsion prepared using the optimal formulation had an entrapping efficiency of 73.25% ± 0.73% and a diameter of 114.52 ± 0.015 nm, with a satisfactory particle size of nanoscale and a PDI of 0.119 ± 0.065, demonstrating good stability of the emulsion.

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Section: Introductionmentioning

confidence: 99%

Antioxidant Activity, Formulation, Optimization and Characterization of an Oil-in-Water Nanoemulsion Loaded with Lingonberry (Vaccinium vitis-idaea L.) Leaves Polyphenol Extract

Wang,

Cheng,

Wang

et al. 2023

Foods

View full text Add to dashboard Cite

show abstract

Comprehensive phytochemical analysis of lingonberry (Vaccinium vitis-idaea L.) from different regions of China and their potential antioxidant and antiproliferative activities

Abstract: Comparative comprehensive chemical profiles of major metabolites of lingonberries from different origins.

Cited by 1 publication

References 41 publications

Antioxidant Activity, Formulation, Optimization and Characterization of an Oil-in-Water Nanoemulsion Loaded with Lingonberry (Vaccinium vitis-idaea L.) Leaves Polyphenol Extract

Antioxidant Activity, Formulation, Optimization and Characterization of an Oil-in-Water Nanoemulsion Loaded with Lingonberry (Vaccinium vitis-idaea L.) Leaves Polyphenol Extract

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