Comprehensive insights into AML relapse: genetic mutations, clonal evolution, and clinical outcomes
Namsoo Kim,
Seungmin Hahn,
Yu Jeong Choi
et al.
Abstract:Introduction
Acute myeloid leukemia (AML) is a complex hematologic malignancy characterized by uncontrolled proliferation of myeloid precursor cells within bone marrow. Despite advances in understanding of its molecular underpinnings, AML remains a therapeutic challenge due to its high relapse rate and clonal evolution.
Methods
In this retrospective study, we analyzed data from 24 AML patients diagnosed at a single institution between January 2017 … Show more
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