Comprehensive framework of factors accounting for worse aortic aneurysm outcomes in females: A scoping review

De Freitas, Simon; Falls, Garietta; Weis, Tahlia; Bakhshi, Kirran; Korepta, Lindsey M.; Bechara, Carlos F.; Erben, Young; Arya, Shipra; Fatima, Javairiah

doi:10.1053/j.semvascsurg.2023.10.007

Cited by 2 publications

(1 citation statement)

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“…The overall hospital mortality in surgically treated nrAAs was 2.0% and lower compared to countries such as the United States or the Netherlands [28,29]. Interestingly, the crude mortality was significantly higher in women than in men, which is in line with most analyses of aortic surgery [7,[29][30][31][32]. However, a multivariable analysis adjusted for the observed age difference and other parameters showed that mortality did not differ significantly between the sexes.…”

Section: Discussionsupporting

confidence: 73%

Hospital Incidence, Sex Disparities, and Perioperative Mortality in Open Surgically Treated Patients with Aneurysms of the Ascending Aorta and Aortic Arch in Switzerland

Menges,

Zimmermann,

Stoklasa

et al. 2024

Healthcare

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Objective. To analyze the epidemiological shifts in the incidence of ascending and arch aortic aneurysms (AA) treated with open surgery in the context of evolving endovascular options on a national basis. Methods. Between 1 January 2009 and 31 December 2018, 4388 cases were admitted to the hospital with either ruptured (r)AA or non-ruptured (nr)AA as the primary or secondary diagnosis. Patients were classified as having AA based on inclusion and exclusion criteria. Results. The age-standardized hospital incidence rates for treatment of nrAA were 7.8 (95% confidence interval (CI): 6.9 to 8.7) in 100,000 men and 2.9 (2.4 to 3.4) in 100,000 women and were stable over time. The overall raw in-hospital mortality rate was 2.0% and was significantly lower in males compared to women (1.6% vs. 2.8%, p = 0.015). Higher van Walraven scores (OR: 1.08 per point; 95%CI: 1.06 to 1.11; p = 0.001) and higher age (OR 1.05 per year; (95%CI: 1.02 to 1.07, p = 0.045) were significantly associated with hospital mortality. Conclusions. Endovascular surgery seems to have no influence on hospital incidence in patients treated with conventional surgery for AA in Switzerland. There was a significant reduction in in-hospital mortality in both men and women, with age and the von Walraven score being independent factors for worse outcomes.

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