Abstract:Background: MEF-2 family was associated with the pathogenesis of cancers. The crucial roles of MEF-2 family members in gastric cancer (GC) have been demonstrated. However, the underlying mechanisms remain unclear.Methods: Our study profiles the variance of four MEF2 genes in GC from genomic, epigenomic, and transcriptome angles. Iterative weight gene co-expression network analysis (WGCNA) was applied to identify the MEF2-related module and hub genes. enrichment analysis was conducted for MEF2-related hub genes… Show more
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