Comprehensive analysis of the cerebrospinal fluid and serum metabolome in neurological diseases
Carolin Otto,
Rea Kalantzis,
Dorothee Kübler-Weller
et al.
Abstract:Background
Comprehensive characterization of the metabolome in cerebrospinal fluid (CSF) and serum by Nuclear Magnetic Resonance (NMR) spectroscopy may identify biomarkers and contribute to the understanding of the pathophysiology of neurological diseases.
Methods
Metabolites were determined by NMR spectroscopy in stored CSF/serum samples of 20 patients with Parkinson’s disease, 25 patients with other neuro-degenerative diseases, 22 patients with c… Show more
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