“…In turn, the activated LINEs and their expressed products may help the virus integrate into the host. Others however have both questioned the methodology of the work [44] or found little evidence for SARS-CoV-2 integration into the genome of infected individuals [45] raising questions about the solidity of the other findings. Interestingly however, in terms of the ability of a virus to stimulate LINE-1 activity, previous studies examined the effect of the Kaposi's sarcoma (KS)associated herpesvirus (KSHV) on L1 retrotransposition [46,47].…”