Comprehensive analysis of DNA methylation gene expression profiles in GEO dataset reveals biomarkers related to malignant transformation of sinonasal inverted papilloma
Li Mu,
Shun Hu,
Guoping Li
et al.
Abstract:Background
DNA methylation may be involved in the regulation of malignant transformation from sinonasal inverted papilloma (SNIP) to squamous cell carcinoma (SCC). The study of gene methylation changes and screening of differentially methylated loci (DMLs) are helpful to predict the possible key genes in the malignant transformation of SNIP-SCC.
Materials and methods
Microarray dataset GSE125399 was downloaded from the Gene Expression Omnibus (GEO)… Show more
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