Comprehensive analysis and prediction model of mitophagy and ferroptosis in primary immune thrombocytopenia
Jiani Mo,
Yong Liu,
Wencong Zhang
et al.
Abstract:SummaryPrimary immune thrombocytopenia (ITP) is linked to specific pathogenic mechanisms, yet its relationship with mitophagy and ferroptosis is poorly understood. This study aimed to identify new biomarkers and explore the role of mitophagy and ferroptosis in ITP pathogenesis. Techniques such as differential analysis, Mfuzz expression pattern clustering, machine learning, gene set enrichment analysis, single‐cell RNA sequencing (scRNA‐seq) and immune infiltration analysis were employed to investigate the mole… Show more
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