Comprehension of premarital screening and genetic disorders among the population of Riyadh

AlOtaiby, Shahad; Alqahtani, Abdulhadi M.; Saleh, Ruba; Mazyad, Abeer; Albohigan, Abdulrazaq; Kutbi, Emad

doi:10.1016/j.jtumed.2023.01.006

Cited by 4 publications

(6 citation statements)

References 19 publications

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“…319 (33.2%) were from stage 4, and 280 (29.2%) were from stage 1. The median and interquartile range was 3 (3), as shown in Table 1.…”

Section: Resultsmentioning

confidence: 99%

Knowledge, perception, and attitude toward premarital screening among university students in Kurdistan region- Iraq

Mahmood,

Sadraldeen,

Othman

et al. 2024

Preprint

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BackgroundPremarital screening programs are essential for identifying and providing counseling to couples at risk of transmitting genetic diseases or sexually transmitted infections. Despite their importance, university students’ awareness and knowledge of premarital screening programs remain inadequate. This study aimed to evaluate the knowledge, perceptions, and attitudes of university students in the Kurdistan Region of Iraq regarding premarital screening programs.MethodsA cross-sectional survey involving 960 students was conducted from December 2023 to February 2024. The survey assessed participants’ demographics, knowledge, perception, and attitudes toward PMSP using a structured questionnaire.ResultsFindings revealed that a significant portion of participants (39.4%) had poor knowledge of premarital screening programs, 35.9% had fair knowledge, and only 24.7% had good knowledge. Despite limited knowledge, there was strong support for premarital screening programs, with 83.1% agreeing on its importance and 78.8% recognizing the need for premarital awareness. Most participants (65.8%) believed premarital screening programs could reduce genetic diseases, and 65.6% thought it could lower sexually transmitted diseases’ prevalence. Cultural acceptance of marrying relatives was notable, with 59.7% disagreeing with the preference for not marrying relatives. Married participants showed significantly higher knowledge and attitude scores compared to single participants. Gender differences were observed, with males having higher knowledge scores. There were no significant differences in perception and attitude scores based on gender or residential area.ConclusionThe study underscores the need for enhanced educational campaigns to improve premarital screening programs awareness and positively influence attitudes, especially targeting cultural aspects like accepting relative marriages. Comprehensive education and fostering positive attitudes toward premarital screening programs are vital for their broader acceptance and implementation.

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“…319 (33.2%) were from stage 4, and 280 (29.2%) were from stage 1. The median and interquartile range was 3 (3), as shown in Table 1.…”

Section: Resultsmentioning

confidence: 99%

Knowledge, perception, and attitude toward premarital screening among university students in Kurdistan region- Iraq

Mahmood,

Sadraldeen,

Othman

et al. 2024

Preprint

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“…Research indicates that individuals diagnosed with genetic diseases may be more susceptible to experiencing PMS than those without such a diagnosis ( 38 , 39 ). It is a strong predictor of perceived susceptibility among participants and is consistent with existing literature ( 21 ).…”

Section: Discussionmentioning

confidence: 99%

Health beliefs of unmarried adult Saudi individuals toward safe marriage and the role of premarital screening in avoiding consanguinity: a nationwide cross-sectional study

Alwhaibi,

Almuwais,

Alotaibi

et al. 2024

Front. Public Health

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IntroductionPremarital screening (PMS) is an essential global measure that seeks to reduce the occurrence of specific genetic disorders and sexually transmitted diseases common in consanguineous marriages. Due to the lack of a nationwide study, this research was designed to comprehend how unmarried individuals perceive the risks and benefits of PMS.MethodA cross-sectional study was conducted using an online questionnaire distributed through different social media platforms, responses from the native adult population (18–49 years) Saudi Arabia was only included in the study. The questionnaire was based on the Health Belief Model (HBM) to assessing seven different constructs including susceptibility, seriousness, benefits-, barriers-, & cues- to action, self-efficacy, and social acceptance. Data frequency was represented by mean and standard deviation; chi-square and t-tests were conducted for the comparison of independent and dependent variables. A multinomial logistic regression was used to predict factors influencing decisions related to PMS.Results1,522 participants completed the survey, mostly 18–25 years old and most of them were women. The majority were single with 85 men and 1,370 women. Most participants (59.6%) believed their parents were related, while 40.5% did not. 122 respondents reported they had to marry within their tribe. Findings revealed significant correlations among all HBM themes, with varying strengths. Notably, a moderate positive relationship was found between the perception of benefits and cues to action, suggesting that enhancing the perceived benefits of PMS could facilitate safe marriage practices. Multinomial regression analysis revealed that demographic factors and health beliefs significantly influence individuals’ intentions and behaviors toward PMS and safe marriage.ConclusionThe study concludes that by identifying and addressing barriers, and promoting positive social acceptance, PMS can significantly contribute to preventing genetic diseases and promoting safe marriage practices, although the cross-sectional design limits the establishment of causal relationships and further research is needed.

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“…Untuk menghindari kelahiran anak dengan kelainan gen tunggal atau kelainan kromosom, maka penting untuk melakukan skrining pra-nikah, agar dapat diketahui apakah seseorang yang akan menikah merupakan pembawa kelainan, sehingga mengurangi resiko kelahiran anak dengan kelainan genetik. Skrining pra-nikah pada umumnya menyusur individu-individu yang belum menikah, karena persepsi dan tindakan mereka dapat mempengaruhi kehidupan mereka, terutama dalam memilih pasangan sehingga mempengaruhi kualitas kehidupan pernikahan dan kesehatan generasi penerus mereka kelak (AlOtaiby et al, 2023).…”

Section: IIIunclassified

“…Kelainan genetik umum ditemukan dan menjadi perhatian karena berhubungan dengan morbiditas dan mortalitas di negara-negara Arab. Salah satu yang memberikan kontribusi utama pada tingginya insidensi kelainan genetik pada darah (thalassemia) di negara-negara Arab adalah banyaknya pernikahan antar kerabat (Al-Enezi & Mitra, 2017;Alhowiti & Shaqran, 2019;Ibrahim et al, 2011), sehingga deteksi pembawa kelainan genetik atau kelainan keturunan pada negara-negara ini merupakan strategi untuk mengontrol prevalensinya (AlOtaiby et al, 2023).…”

Section: IIIunclassified

Pengetahuan dan Pendapat Mahasiswa Poltekkes Surabaya Tentang Kelainan Genetik dan Skrining Pra-Nikah

Wulandari,

Setijowati

2024

comdev

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To ensure couples planning to get married understand the genetic risks related with their future offspring, they need to acquire information about genetic disorders and pre-marital genetic counselling that can be followed by genetic screening. Genetic disorders can be inherited from normal parents who are carriers of abnormal genes, such as thalassemia and Haemophilia. Genetic disorder also encompass chromosomal abnormalities, either the number or structure chromosome. Unlike numerical chromosomal abnormalities in offspring, which have an increased risk associated with the mother’s age during pregnancy, structural abnormalities in parents can be passed to their offspring. This community service activity targets seventh-semester students at Poltekkes Kemenkes Surabaya, who are at an age ready for marriage. The implementation of this activity begins with a pre-test to assess the student ‘s knowledge before the education presentation, followed by presentation with interactive discussion and ended with post-test to determine whether the education was comprehensible to them. Poltekkes Kemenkes Surabaya students showed a better understanding of genetic disorder indicated with an average score increase of 8.2 points (9.2%) based on post test result . All students agree on the importance of pre-marital screening, with the majority willing to undergo premarital screening and still proceed with the marriage if their partner is a carrier of thalassemia.

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Comprehension of premarital screening and genetic disorders among the population of Riyadh

Cited by 4 publications

References 19 publications

Knowledge, perception, and attitude toward premarital screening among university students in Kurdistan region- Iraq

Knowledge, perception, and attitude toward premarital screening among university students in Kurdistan region- Iraq

Health beliefs of unmarried adult Saudi individuals toward safe marriage and the role of premarital screening in avoiding consanguinity: a nationwide cross-sectional study

Pengetahuan dan Pendapat Mahasiswa Poltekkes Surabaya Tentang Kelainan Genetik dan Skrining Pra-Nikah

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