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Cited by 5 publications
(5 citation statements)
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“…C) mutation with (db) 0 thalassemia influences the upregulation of c gene. Similar findings are reported by Dehury et al [6] and Pandey et al [7]. However, in case of compound heterozygotes reported by Pandey et al [7] both Hb A2 and HB F were significantly lower than in the present case.…”
supporting
confidence: 91%
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“…C) mutation with (db) 0 thalassemia influences the upregulation of c gene. Similar findings are reported by Dehury et al [6] and Pandey et al [7]. However, in case of compound heterozygotes reported by Pandey et al [7] both Hb A2 and HB F were significantly lower than in the present case.…”
supporting
confidence: 91%
“…However, in case of compound heterozygotes reported by Pandey et al [7] both Hb A2 and HB F were significantly lower than in the present case. Our report is comparable to the report of Dehury et al [6]. Further among the two siblings one showed facial bone deformities and abdominal swelling not visible in the other.…”
supporting
confidence: 91%
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“…Usually in β + β 0 type βthalassemia, the Hb pattern shows HbA between 10 and 30%, HbF of 70-90% and HbA2 of 2-5%. [46] Murali et al (2004) have checked the prevalence of different mutations in different districts of Andhra Pradesh and Karnataka. [47] They can observe that IVS1+5G>T mutation is the most popular around Andhra Pradesh and Karnataka.…”
Section: Discussionmentioning
confidence: 99%
“…In the present case, the compound heterozygosity has lead to β + β 0 type causing β-thalassemia major. Usually in β + β 0 type β-thalassemia, the Hb pattern shows HbA between 10 and 30%, HbF of 70–90% and HbA2 of 2–5% [12] .…”
Section: Discussionmentioning
confidence: 99%