Novel material has been synthesized from the hydroxyapatite (HAp) nanopowder by chemical precipitation method in mesopores of activated carbon AC, forming HAp-C. Recently novel compositions in this system HAp-C were described and characterized with regard to DTA,SEM, S BET, S α t , S α n V P , V u, V ot, and V os,. These studies showed that these novel HAp-C compounds are suitable for bone fabrication. Thus heat treatment of the mixed HAp-C can be applied to increase the crystallinity without creating stresses between the coating and the underlying HAp-C. The degradation and durability of carbon is reviewed in the presence of nanoparticles/ nanocomposites under different environmental conditions. For all products, poorly crystalline apatite phases were obtained after drying, exhibiting a mesoporous structure with specific surface area up to 150m 2 g−1. These materials could be converted into a pure crystalline of hydroxyapatite-carbon at 800 0 C. The use of surface science and engineering are relatively new fields of research in which surface characterization has been widely used to design material properties with specific purposes, including biomedical applications.