Compositions and antimicrobial activities of the essential oils of two Hypericum species from Turkey

Toker, Zuhal; Kızıl, Göksel; Özen, Hasan Çetin; Kızıl, Murat; Ertekin, Selçuk

doi:10.1016/j.fitote.2005.08.019

Cited by 30 publications

(13 citation statements)

References 5 publications

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“…Similarly, EO of H. hyssopifolium var. microcalcynum also shown to have activity against this clinical isolate (Toker et al 2006). Cakir and co-workers (Cakir et al 2004) tested the EO of three species of Hypericum against several phytopathogenic fungi using agar diffusion method for the possible use in agricultural pest and disease control (Table 6).…”

Section: Antifungal Activitymentioning

confidence: 99%

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Hypericum sp.: essential oil composition and biological activities

2012

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Phytochemical composition of Hypericum genus has been investigated for many years. In the recent past, studies on the essential oils (EO) of this genus have been progressing and many of them have reported interesting biological activities. Variations in the EO composition of Hypericum species influenced by seasonal variation, geographic distribution, phenological cycle and type of the organ in which EO are produced and/or accumulated have also been reported. Although many reviews attributed to the characterization as well as biological activities of H. perforatum crude extracts have been published, no review has been published on the EO composition and biological activities of Hypericum species until recently (Crockett in Nat Prod Commun 5(9): 1493-1506, 2010 Bertoli et al. in Global Sci Books 5:29-47, 2011). In this article, we summarize and update information regarding the composition and biological activities of Hypericum species EO. Based on experimental work carried out in our laboratory we also mention possible biotechnology approaches envisaging EO improvement of some species of the genus.

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Section: Antifungal Activitymentioning

confidence: 99%

“…As these compounds are widely found in the EO of Hypericum, it is not surprising to see many reports on antimicrobial activities of species of this genus (Gudžić et al 1997;Schwob et al 2002;Couladis et al 2003;Cakir et al 2004;Cakir et al 2005;Schwob et al 2006;Toker et al 2006;Saroglou et al 2007). …”

Section: Antifungal Activitymentioning

confidence: 99%

Hypericum sp.: essential oil composition and biological activities

2012

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“…The essential oils and various extracts of H. triquetrifolium and H. scabroides have been examined for their antiinflammatory and antimicrobial activities (Sokmen et al, 1999;Ozturk et al, 2002;Kizil et al, 2004;Toker et al, 2006). Antioxidant activity of H. hyssopifolium L. was also examined by Cakir et al (2003), and six phenolic compounds have been isolated from the ethyl acetate fraction of a methanol extract of H. hyssopifolium.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Activities of Ethanol Extracts ofHypericum triquetrifolium. andHypericum scabroides.

Kızıl

Yavuz

et al. 2008

Pharmaceutical Biology

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The antioxidative potential of ethanol extracts of Hypericum triquetrifolium Turra (Hypericaceae) and Hypericum scabroides Robson & Poulter (Hypericaceae) were investigated for the first time using 1,1-diphenyl-2-picrylhydrazyl (DPPH), metal chelating, reducing power, hydroxyl radical, total antioxidant activity, and lipid peroxidation inhibition assays. Both extracts tested were found to be highly active in the DPPH radical scavenging assay. The IC 50 values of H. triquetrifolium (HT) and H. scabroides (HS) in the DPPH radical scavenging assay were 39.0 and 33.8 µg/mL, respectively. The amounts of total phenolic compounds were also determined, and total phenolic content of 1 mg H. triquetrifolium and H. scabroides ethanol extracts were equivalent to 267 and 333 µg gallic acid. Metal chelating ability was found to be low compared with EDTA. Both ethanol extracts of Hypericum species exhibited a high reducing power, suggesting that extracts had strong electron-donating capacity. The degradation of deoxyribose by hydroxyl radicals was shown to be inhibited by Hypericum extracts, acting mainly by scavenging hydroxyl radicals rather than as chelators of iron ions. Total antioxidant activity of ethanol extracts of HT and HS were tested by using ferric thiocyanate (FTC) and thiobarbituric acid (TBA) methods. Antioxidative activities of both extracts were found to be comparable with vitamin E. Moreover, both extracts showed notable capacity to suppress Fe 2+ -induced lipid peroxidation in rat brain homogenate. The results obtained in the current study indicate that ethanol extracts of HS and HT are a potential source of natural antioxidants.

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“…microcalycinum and H. lysimachioides var. lysimachioides (Toker et al, 2006). Thirty components representing 92% of the total volatiles were characterized in H. Bupleuroides, and sesquiterpenes such as β-sesquiphellandrene (33.2%) and β-caryophyllene (20.2%) were assigned as major compounds (Demirci and Baser, 2006).…”

Section: Volatile Compoundsmentioning

confidence: 99%