Compositional studies and Biological activities of Perovskia abrotanoides Kar. oils

Abstract

Background Current study has been designed to evaluate the chemical composition of essential and fixed oils from stem and leaves of Perovskia abrotanoides and antioxidant and antimicrobial activities of these oils. Results GC-MS analysis of essential oil identified 19 compounds with (E)-9-dodecenal being the major component in stem and hexadecanoic acid in leaves. In contrast, GC-MS analysis of fixed oil showed 40 constituents with α-amyrin the major component in stem and α-copaene in leaves. The antioxidant activity showed the highest value of 76.7% in essential oil from leaves in comparison with fixed oil from stem (45.9%) through inhibition of peroxidation in linoleic acid system. The antimicrobial assay tested on different microorganisms (e.g. E. coli, S. aureus, B. cereus, Nitrospira, S. epidermis, A. niger, A. flavus and C. albicans ) showed the higher inhibition zone at essential oil from leaves (15.2 mm on B. cereus ) as compared to fixed oil from stem (8.34 mm on S. aureus ) and leaves (11.2 mm on S. aureus ). Conclusions The present study revealed the fact that essential oil analyzed from Perovskia abrotanoides stem and leaves could be a promising source of natural products with potential antioxidant and antimicrobial activities, as compared to fixed oil.

Genetic and Chemical Diversity in Perovskia abrotanoides Kar. (Lamiaceae) Populations Based on ISSRs Markers and Essential Oils Profile

“…The obtained results were similar to the previously published data for the plant from Iran, where 1,8‐cineole, δ ‐3‐carene, camphor, myrcene, and β ‐caryophyllene were identified as the major EOs compounds . Comparing the results obtained in this study with the other reported for samples collected in Pakistan, a noticeable variation in composition and percentages of components can be observed. The major components of P .…”

“…The obtained results were similar to the previously published data for the plant from Iran, where 1,8-cineole, d-3-carene, camphor, myrcene, and b-caryophyllene were identified as the major EOs compounds. [27 -30] Comparing the results obtained in this study with the other reported for samples collected in Pakistan, [71] a noticeable variation in composition and percentages of components can be observed. The major components of P. abrotanoides essential oil from Pakistan (stem and leaves) were (E)-9-dodecenal (66.5%), hexadecanoic acid methyl ester (27.79%), lupeol (21.5%), octadecenoic acid methyl ester (18.45%), eicosane (6.22%), tetradecane (5.19%), octadecanoic acid methyl ester (8.37%), and 2,2,5, 5-tetramethylhexane (3.96%).…”

Variations in Essential Oil Composition and Antioxidant Activity in Perovskia abrotanoides Kar. Collected from Different Regions in Iran

“…Radical scavenging activity values also revealed similar trend (Figure 3b). The results reported by Ashraf et al [38] on the DPPH contents of P. abrotanoides leaves and stems were not comparable with ours, probably due to differences in standards and experimental conditions. [39] However, our results are confirmed by those obtained for seven Salvia species by Aghaei Jeshvaghani et al [36] who reported IC 50 values in the range of 198 lg/ml in S. virgata to 1810 lg/ml in S. persica.…”

“…[40] As shown in Figure 4, the strongest activity (i.e., the lowest EC 50 ) was recorded for PMASA with an EC 50 value of 0.039 mg/ml while PKRGS recorded the lowest. Ashraf et al [38] also reported the highest reducing power in Perovskia leaves. Experimenting with Salvia species, Aghaei Jeshvaghani et al [36] reported reducing powers similar to the ranges observed in the present study.…”

Documentation of Ethnoveterinary Practices in the CKNP Region, Gilgit-Baltistan

“…Cut [S] A sharp cut is made on the ear of the animals. T [72], Seriphidium brevifolium [73] etc. However further details about the phytochemicals from several other plant species are given in Table 9.…”