Compositional, Elemental, Phytochemical and Antioxidant Characterization of Jackfruit (Artocarpus heterophyllus) Pulps and Seeds from Selected Regions in Kenya and Uganda

Ojwang, Redemtor Awuor; Muge, Edward K.; Mbatia, Betty; Mwanza, Benson; Ogoyi, Dorington

doi:10.9734/ejmp/2018/40967

Cited by 12 publications

(6 citation statements)

References 11 publications

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“…Total phenolic content was carried out using a method described by Ojwang et al (2018). The methanol, ethanol, and water sample extract (0.1 ml) were mixed with 3 ml of solvent; 80% methanol, 70% ethanol, and distilled water, respectively.…”

Section: Determination Of Total Phenolic Content (Tpc)mentioning

confidence: 99%

Evaluation of seasonal variation, effect of extraction solvent on phytochemicals and antioxidant activity on Rosmarinus officinalis grown in different agro-ecological zones of Kiambu County, Kenya

et al. 2023

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Background Rosemary (Rosmarinus officinalis) is a commonly used culinary herb with great potential applications in the pharmaceutical, food, and cosmetics industries because of its reported bioactive phytochemicals and antioxidant properties. The purpose of the study was to investigate the effect of seasonal variations in different agro-ecological zones (AEZs) on the phytochemical content and corresponding antioxidant activities of R. officinalis, to ascertain the best growth period at which the plant possesses the highest phytochemical components and most potent antioxidant property. The study also aimed at comparing different extraction solvents to establish the best extraction system for the bioactive compounds. Methods The leaves of R. officinalis were harvested from six purposively selected sites in four agro-ecological zones of Kiambu County, Kenya both in the wet and the dry seasons. Phytochemicals were extracted in 80% methanol, 80% ethanol, and distilled water. Total phenolic content (TPC), total flavonoids content (TFC), and total tannins content (TTC) were measured spectrophotometrically as gallic acid equivalent (GAE), rutin equivalent (RUTE) and tannic acid equivalent (TAE), respectively. The antioxidant activities were measured using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric-reducing antioxidant power (FRAP). The 80% ethanolic solvent was used to compare the phytochemical content and corresponding antioxidant activities of R. officinalis leaf samples collected from two consecutive seasons in different agro-ecological zones. Results The solvents showed no significant difference (P > 0.05) in TPC with ethanol repotting the highest followed by methanol and water ranging from 39.71 ± 6.77, 24.91 ± 5.15 and 24.91 ± 7.30 (mg/g GAE), respectively. The aqueous TFC (117.22 ± 3.64 mg/g RUTE) was the highest followed by ethanolic and methanolic with 34.72 ± 2.13 and 16.86 ± 2.80 mg/g RUTE, respectively. The TTC of water, methanol, and ethanol extracts were; 19.88 ± 4.59, 15.02 ± 1.25, and 4.27 ± 1.48 mg/g TAE, respectively. The DPPH activity between methanol and ethanol extracts showed no significant difference. The FRAP activity also showed no significant difference (P > 0.05) among the three solvents. There were significant differences between the wet and dry seasons in the phytochemical content. There was no recorded significant difference in the DPPH activity between the dry and wet season in all AEZs. FRAP was significantly higher in the dry season than the wet season for R. officinalis leaves harvested in all agro-agroecological zones except Thika. There were significant differences in phytochemical content and antioxidant activity between the agro-ecological zones (p < 0.05) except for the TFC. Conclusions The data obtained from this study demonstrated that hydro-alcoholic /methanolic and aqueous maceration systems extracted bioactive compounds from R. officinalis with high potential for applications in industries. The R. officinalis from different agro-ecological zones contained variable phytochemical composition, suggesting that geographical location and climatic conditions influence the biosynthesis and accumulation of secondary metabolites and other bioactive compounds. The data provided in this study will be crucial for processors to select the optimal harvesting season for the extraction of desired bioactive compounds from Rosmarinus officinalis.

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Section: Determination Of Total Phenolic Content (Tpc)mentioning

confidence: 99%

Evaluation of seasonal variation, effect of extraction solvent on phytochemicals and antioxidant activity on Rosmarinus officinalis grown in different agro-ecological zones of Kiambu County, Kenya

et al. 2023

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“…[14] The AH [ Figure 1] contains various chemical constituents, i.e., artocarpin, artocarpetin, norartocarpetin, atropine, cycloartinone morin, dihydromorin, cynomycin, and artocarpanone. [15] The AH may contains albumin 1.7%, cellulose 59.0%, lipid 1.7%, moisture 6.7%, and glycosides 38.0%, [16,17] root contains β-sitosterol, ursolic acid, betulinic acid, and cycloartenone, [18] and latex is used as an anti-inflammatory agent. [19] MK is identified as curry leaf [ Figure 2].…”

Section: Plant Materials Collection and Authenticationmentioning

confidence: 99%

Untitled

2020

IJPBA

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The aim of the paper is to assess the anti-inflammatory potential of three medicinal plants using two rat models. Materials and Methods: Soxhlet extraction approaches utilized to separate the constituents of interest. Quantitative analysis has been performed to determine the total phenolic and flavonoid content. Three plants extract employed for the ointment formulation by addition of the extract of Artocarpus heterophyllus (AH), Murraya koenigii (MK), and Punica granatum (PG) in polyethylene glycol (PEG) ointment base, a blend of PEG 600 and PEG 4000, and ratio 7:3, respectively. Two rat models based on chemical induced animals employed for the anti-inflammatory potential. Results and Discussion: All three plants including AH Lam., MK Linn., and PG Linn. extracted for the major component and have shown the gallic acid and quercetin as major component for flavonoid and phenol content. The ointment formulation F3 has showed maximum inhibition (80.95%) at 50 mg/kg dose of carrageenan-induced edema and 83.33% inhibition at 100 mg/kg dose. The ointment formulation F3 has showed maximum inhibition (78.57%) at 50 mg/kg dose of histamine persuade edema and 83.33% inhibition at 100 mg/kg dose. F3 ointment formulation is better than the F2 and F1 formulation in inhibition and in all phases showing its reserve of kinins as well as arachidonic acid. Conclusion: Quantitative and pharmacological evaluation indicated that ointment formulations of AH, MK, and PG have exploit for anti-inflammatory activity. The normal extract has shown the least activity but ointment formulations have shown the better result. The ointment formulations containing plant extracts in 10% amount have better wound healing potential.

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“…The leaves and stem show the presence of sapogenins, cycloartenone, cycloartenol, β-sitosterol and tannins, they show estrogenic activity. A root contains βsitosterol, ursolic acid, betulinic acid and cycloartenone 4 . (Figure 3), called curry leaf, is a small, tropical to sub-tropical tree or shrub that typically grows to 6-15' tall and is noted for its pungent, aromatic, curry leaves which are an important flavoring used in Indian/Asian cuisine.…”

Section: Artocarpus Heterophyllus Lam: Artocarpus Heterophyllusmentioning

confidence: 99%

Development, characterization and evaluation of poly-herbal ointment and Gel formulation containing Nerium Indicum Mill, Artocarpus Heterophyllus Lam, Murraya Koenigii Linn, Punica Granatum Linn

Shukla¹,

Kashaw²

2019

J. Drug Delivery Ther.

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Objective: The objective of present study was the development, characterization and evaluation of poly-herbal ointment and gel formulations of Nerium Indicum Mill, Artocarpus Heterophyllus Lam, Murraya Koenigii Linn, Punica Granatum Linn extract. Plant derived substances and herbal medicines have recently attracted the great interest towards their versatile application. Medicinal plants are the richest source of bioactive compounds used in traditional and modern medicine. The ointment and gel formulation of plant extract has a sound approach, The poly-herbal ointment and gel formulation were evaluated for its physicochemical parameters like color, odour, pH, spreadability, extrudability, consistency, diffusibility, solubility, washability, non-irritancy and stability. Materials and methods: Extract of all four plants has been separated by the soxhlet extraction by 70% ethanol. Poly-herbal ointment and gel formulation has been prepared by mixing the extract of Nerium Indicum Mill, Artocarpus Heterophyllus Lam, Murraya Koenigii Linn, Punica Granatum Linn with carbapol 940 for Gel formulation and PEG 2000 & PEG 600 for ointment formulation. Results and conclusion: Physicochemical evaluation shows that the poly-herbal ointment and gel formulations fulfilled the criteria as herbal formulation and irritancy test also performed to indicate the effectiveness and efficacy of prepared ointment and gel formulations. The poly-herbal ointment and gel formulations were also evaluated for its stability at various temperature conditions which shows no change in the irritancy, spreadability and diffusion study. Thus it could become a medium to use the medicinal properties of extracts effectively and easily as a simple dosage form. Keywords: Nerium Indicum Mill, Artocarpus Heterophyllus Lam, Murraya Koenigii Linn, Punica Granatum Linn, extract, ointment, gel.

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Compositional, Elemental, Phytochemical and Antioxidant Characterization of Jackfruit (Artocarpus heterophyllus) Pulps and Seeds from Selected Regions in Kenya and Uganda

Cited by 12 publications

References 11 publications

Evaluation of seasonal variation, effect of extraction solvent on phytochemicals and antioxidant activity on Rosmarinus officinalis grown in different agro-ecological zones of Kiambu County, Kenya

Evaluation of seasonal variation, effect of extraction solvent on phytochemicals and antioxidant activity on Rosmarinus officinalis grown in different agro-ecological zones of Kiambu County, Kenya

Untitled

Development, characterization and evaluation of poly-herbal ointment and Gel formulation containing Nerium Indicum Mill, Artocarpus Heterophyllus Lam, Murraya Koenigii Linn, Punica Granatum Linn

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