Composition of the essential oils of wild and cultivated <i>Satureja khuzistanica</i> Jamzad from Iran

Farsam, Hassan; Amanlou, Massoud; Radpour, M. R.; Salehinia, A. N.; Shafiee, Abbas

doi:10.1002/ffj.1300

Cited by 74 publications

(53 citation statements)

References 6 publications

(5 reference statements)

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“…Essential oils are originating in aromatic plants and have volatile fractions that are responsible for biological activity, smell, and taste (12). Reviews have reported that the main constituents of S. khuzestanica essential oil (SKEO) in the majority species are phenols, carvacrol, thymol, p-cymene, b-caryophyllene, linalool, monoterpenes, sesquiterpenes, alcohols and phenolic acids (7,12).…”

Section: Introductionmentioning

confidence: 99%

“…Reviews have reported that the main constituents of S. khuzestanica essential oil (SKEO) in the majority species are phenols, carvacrol, thymol, p-cymene, b-caryophyllene, linalool, monoterpenes, sesquiterpenes, alcohols and phenolic acids (7,12). On the other hand, it has been previously proven that the chemical composition of essential oils is directly depended on some factors such as the geographical source and harvesting time (13,14).…”

Section: Introductionmentioning

confidence: 99%

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Chemical composition, acute and sub-acute toxicity of Satureja khuzestanica essential oil in mice

Fallahi¹,

Beyranvand²,

Mahmoudvand³

et al. 2017

Marmara Pharmaceutical Journal

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To date, herbal medicines are the important source in the development of new drugs to remedy various diseases. However, it is crucial to provide scientific justification of these drugs to determine their side effects in treatments. This study was aimed to evaluate the chemical composition, acute and subacute toxicity of Satureja khuzestanica essential oil (SKEO) in a mice model. Plant materials of S. khuzestanica were collected from the rural regions of Lorestan Province, west of Iran. Gas chromatography/mass spectrometry (GC/MS) analysis was performed to determine the main components of SKEO. To assess the acute toxicity, 0.5, 1, 2 and 4 ml/kg doses of SKEO were injected intraperitoneally into four groups of six mice. The number of deaths was counted at 24 h after the treatment. Sub-acute toxicity of the effects of SKEO was evaluated by determine the clinical chemistry and hematological parameters of the treated mice after oral administration of SKEO at the doses of 0.2, 0.4 and 0.6 ml/kg, respectively, for 14 consecutive days. Twenty-three compounds were identified in SKEO by GC/MS analysis, in which the main component was carvacrol (64.4%). The LD50 value of intraperitoneal injection of SKEO was 1.79 ml/kg and the maximum nonfatal dose was 1.13 ml/ kg. No death was observed at the doses of 0.2 and 0.4 ml/kg, while in the group receiving 0.8 ml/kg of SKEO, only one mouse died (12.5%). There was no significant difference between the biochemical and hematological parameters following the oral administrations of SKEO at the used doses of 0.2, 0.4 and 0.8 ml/ kg and the controls (P>0.05). The obtained results in this work showed that SKEO at the tested doses had no significant toxicity on the liver and kidney tissues as well as on the hematological parameters in the mice. Therefore, SKEO could be safe for the mammalian host at the used doses.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Chemical composition, acute and sub-acute toxicity of Satureja khuzestanica essential oil in mice

Fallahi¹,

Beyranvand²,

Mahmoudvand³

et al. 2017

Marmara Pharmaceutical Journal

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“…A considerable level of essential oils, up to 4.5%, has been identified as a prominent characteristic for this plant (Hadian et al, 2011). The essential oils of Satureja khuzistanica (EOSk) were reported to be peculiarly rich in carvacrol (Farsam et al, 2004). It has been also shown that EOSk contains a spectrum of phenols, flavones, triterpenoids, steroids, and tannins (Moghaddam et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

The effect of savory (<i>Satureja khuzistanica</i>) essential oils on performance, liver and kidney functions in broiler chickens

Khosravinia¹,

Ghasemi²,

Alavi³

2013

J. Anim. Feed Sci.

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“…Savory (Satureja khuzistanica) is an annual, herbaceous aromatic and medicinal plant belonging to the Lamiaceae family with identified essential oils named carvacrol and thymol [5] .…”

Section: öZetmentioning

confidence: 99%

Broyler Piliçlerde Rasyona Katılan Geyikotu Esansiyel Yağının Aflatoksin B1 Toksisitesinin Azaltılmasındaki Etkinliği

Sadeghi¹,

Mohamadi-Saei²,

Ahmadvand³

2014

Kafkas Univ Vet Fak Derg

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The aim of this study was to evaluate the capability of savory essential oil in counteracting the deleterious effects of aflatoxin B 1 (AFB 1 ) on growth performance, serum biochemistry, and humoral immune responses in broiler chickens fed 42 days of age. At a 2 2 factorial arrangement in completely randomized design, 300 day-old broiler chicks were assigned to four treatments with five replicates of 15 birds. Chickens were fed the basal diet up to day 7 of age and then fed the experimental diets. The dietary treatments involved of 0 and 0.5 mg of AFB1/kg with or without 500 mg of savory/kg dry matter. The addition of aflatoxin to diet decreased (P<0.05) the weight gain and feed intake and resulted in a poor feed conversion ratio. Birds in the AFB 1 group had lower level of albumin, but higher levels of creatinine and liver enzymes in the serum as compared with the control group. The addition of savory to the contaminated diet diminished (P<0.05) the inhibitory effects of dietary AFB 1 on the growth performance and the level of liver enzymes in serum. The addition of aflatoxin to diet caused a decrease and savory supplementation caused an increase in antibody titer against the Newcastle virus, and interaction among the factors was differ (P<0.05). The main effects and interaction on antibody titer against influenza virus were not differ (P>0.05). The addition of savory reduced the adverse effects of aflatoxin on growth performance and provided slight positive effect on serum biochemistry and humoral immune responses in broilers exposed aflatoxin. Keywords: Aflatoxin, Broiler, Savory, Protection Broyler Piliçlerde Rasyona Katılan Geyikotu Esansiyel YağınınAflatoksin B 1 Toksisitesinin Azaltılmasındaki Etkinliği ÖzetBu çalışma, 42 gün süreyle beslenen broyler piliçlerde yeme katılan geyioktu esansiyel yağının, aflatoksin B 1 (AFB 1 )'in büyüme performansı, serum biyokimyası ve hümoral immün yanıtlar üzerine olan zararlı etkilerini yoketme kapasitesinin değerlendirilmesi amacıyla yapıldı. Randomize tasarım ile 2 2 faktöryel düzenlemede, 300 günlük broyler piliçler 15 kanatlı içeren beş tekrarlı dört tedavi grubu olacak şekilde ayarlandı. Piliçler 7. güne kadar temel rasyon ve daha sonra deneysel diyet ile beslendi. Besinsel tedaviler 500 mg kuru madde olarak geyioktu/kg içeren veya içermeyen 0 ve 0.5 mg AFB 1 /kg'dan oluştu. Rasyona aflatoksin eklenmesi ağırlık kazancını ve yem tüketimini azaltırken (P<0.05) zayıf bir yem dönüşüm oranıyla (poor feed conversion ratio) sonuçlandı. AFB 1 grubundaki kanatlıların kontrol grubuyla kıyaslandığınıda düşük albumin düzeyine, fakat yüksek serum kreatin ve karaciğer enzimleri düzeyine sahip olduğu gözlemlendi. Kontamine rasyona geyioktu ilavesinin besinsel AFB1'in büyüme performansı ve serumdaki karaciğer enzim seviyesi üzerindeki inhibitör etkilerini azalttığı (P<0.05) belirlendi. Newcastle virüsüne karşı gelişen antikor titresinin rasyona aflatoksin ilavesi ile azaldığı ve geyioktu ilavesi ile arttığı ve faktörler arası etkileşimin farklı (P<0.05) olduğu gözlemlendi. İnfluen...

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Composition of the essential oils of wild and cultivated Satureja khuzistanica Jamzad from Iran

Cited by 74 publications

References 6 publications

Chemical composition, acute and sub-acute toxicity of Satureja khuzestanica essential oil in mice

Chemical composition, acute and sub-acute toxicity of Satureja khuzestanica essential oil in mice

The effect of savory (<i>Satureja khuzistanica</i>) essential oils on performance, liver and kidney functions in broiler chickens

Broyler Piliçlerde Rasyona Katılan Geyikotu Esansiyel Yağının Aflatoksin B1 Toksisitesinin Azaltılmasındaki Etkinliği

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