Composition of cerebrospinal fluid in clinically normal adult ferrets

Platt, Simon R.; Dennis, Patricia M.; McSherry, Leo J.; Chrisman, C. L.; Bennett, R. Avery

doi:10.2460/ajvr.2004.65.758

Cited by 15 publications

(4 citation statements)

References 12 publications

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“…To avoid this effect, echogenic needles were developed but, unfortunately, they were not available in our institution during the study. Based on the fact that the puncture of the cisterna magna using a hypodermic needle was previously described in different mammal species, including the rabbit, and being a good visualization of the needle necessary during the procedure, the hypodermic needle was preferred to the spinal needle for the main part of the study. To the authors’ knowledge, no studies have been performed to investigate the difference in echogenicity and ultrasound visibility between spinal and hypodermic needles, but this was beyond the aim of our study.…”

Section: Discussionmentioning

confidence: 99%

Ultrasonographic anatomy of the atlanto‐occipital region and ultrasound‐guided cerebrospinal fluid collection in rabbits (Oryctolagus cuniculus)

Anselmi

Dias

Martorell

et al. 2017

Vet Radiology Ultrasound

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Cerebrospinal fluid analyses are important for diagnosis of neurologic problems in rabbits and for translational research projects using rabbits as models. Blind puncture of the cisterna magna is the current standard technique for sampling cerebrospinal fluid in this species. However, the complexity and small size of the cisterna magna and surrounding structures are limitations of this technique. Aims of this prospective, anatomic, pilot study were to (1) describe the normal anatomy of the atlanto-occipital region, (2) describe ultrasonographic anatomic landmarks, and (3) develop and evaluate a technique for ultrasound-guided puncture of the cisterna magna for cerebrospinal fluid sampling in rabbits. Thirty healthy rabbits were included and the study was conducted in three stages. Three rabbit cadavers were used for the first stage of the study. Then, the second stage was completed using 13 rabbit cadavers. Finally, the third stage was completed in 14 live rabbits. The ultrasound-guided puncture performed in 13 cadavers was successful at the first attempt in 10 cases, and at the second attempt in the remaining three cases. In the in vivo study, the ultrasound-guided puncture was successful in all 14 cases, without signs of complications. Findings supported the use of ultrasound-guided puncture of the cisterna magna as a safe technique that may be used routinely or when the sample of cerebrospinal fluid cannot be obtained with the blind technique in rabbits.

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Section: Discussionmentioning

confidence: 99%

Ultrasonographic anatomy of the atlanto‐occipital region and ultrasound‐guided cerebrospinal fluid collection in rabbits (Oryctolagus cuniculus)

Anselmi

Dias

Martorell

et al. 2017

Vet Radiology Ultrasound

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“…10-3). 37 Some spinal lesions may be amenable to surgical resection or stabilization; many, however, carry a poor prognosis. Sites for CSF tap and myelography are the atlanto-occipital and the lumbar (L5-L6) regions.…”

Section: Diagnosis Of Posterior Paresis Ataxia and Seizuresmentioning

confidence: 99%

Musculoskeletal and Neurologic Diseases

Antinoff¹,

Giovanella²

2012

Ferrets, Rabbits, and Rodents

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“…Survey spinal radiographs revealed a mildly narrowed intervertebral disc space between the second and third lumbar vertebrae (Fig 1). Cerebrospinal fluid (CSF) obtained from the cisterna magna revealed a cell count of 2 nucleated cells/μl (range, 0 to 8 nucleated cells/μl), containing mononuclear cells only (Platt and others 2004). Protein concentration in the CSF was not measured due to the small amount of fluid obtained.…”

Section: Case Historymentioning

confidence: 99%

Successful medical management of lumbar intervertebral disc prolapse in a ferret

Srugo

Chai

Yaakov

et al. 2010

J of Small Animal Practice

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Thoracolumbar disc herniation was diagnosed in a two-year-old ferret using a myelogram followed by a computed tomography scan. The ferret was paraplegic with no control over urination and defecation. Conservative treatment that included cage rest and passive range of motion exercises for three weeks followed by extensive physiotherapy and hydrotherapy resulted in full recovery two months after the onset of treatment. Although intervertebral disc disease has been reported previously in four ferrets, this is the first report in which a postmyelogram computed tomography was used to demonstrate the herniated disc, and physiotherapy was used as principal treatment modality.

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Composition of cerebrospinal fluid in clinically normal adult ferrets

Cited by 15 publications

References 12 publications

Ultrasonographic anatomy of the atlanto‐occipital region and ultrasound‐guided cerebrospinal fluid collection in rabbits (Oryctolagus cuniculus)

Ultrasonographic anatomy of the atlanto‐occipital region and ultrasound‐guided cerebrospinal fluid collection in rabbits (Oryctolagus cuniculus)

Musculoskeletal and Neurologic Diseases

Successful medical management of lumbar intervertebral disc prolapse in a ferret

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