Composition and antimicrobial activity of the essential oil of <i>Hypericum maculatum</i> Crantz

Gudžić, Branislav; Djokovic, Dejan; Vajs, Vlatka; Palić, Radosav; Stojanović, Gordana

doi:10.1002/ffj.1112

Cited by 50 publications

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References 4 publications

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“…microcalycinum Chaix., H. Lysimachioides Boiss var. lysimachioides [49], H. Scabroides Robson & Poulter, H. triquetrifolium Turra [50], H. maculatum Crantz [51], H. perforatum L. [52], H. hirsutum L. [53] and H. cordatum Vell. [54].…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of the cytotoxic effect and antibacterial, antifungal, and antiviral activities of Hypericum triquetrifolium Turra essential oils from Tunisia

Rouis

Abid

Koudja

et al. 2013

BMC Complement Altern Med

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BackgroundA number of bio-active secondary metabolites have been identified and reported for several Hypericum species. Many studies have reported the potential use of the plant extracts against several pathogens. However, Hypericum triquetrifolium is one of the least studied species for its antimicrobial activity. The aim of the present study was to evaluate the cytotoxic effect of the essential oils of Hypericum triquetrifolium as well as their antimicrobial potential against coxsakievirus B3 and a range of bacterial and fungal strains.MethodsThe essential oils of Hypericum triquetrifolium harvested from five different Tunisian localities (Fondouk DJedid, Bou Arada, Bahra, Fernana and Dhrea Ben Jouder) were evaluated for their antimicrobial activities by micro-broth dilution methods against bacterial and fungal strains. In addition, the cytotoxic effect and the antiviral activity of these oils were carried out using Vero cell lines and coxsakievirus B3.ResultsThe results showed a good antibacterial activities against a wide range of bacterial strains, MIC values ranging between 0.39-12.50 mg/ml and MBC values between 1.56-25.0 mg/ml. In addition, the essential oils showed promising antifungal activity with MIC values ranging between 0.39 μg/mL and 12.50 μg/mL; MFC values ranged between 3.12 μg/mL and 25.00 μg/mL; a significant anticandidal activity was noted (MIC values comprised between 0.39 μg/mL and 12.50 μg/mL). Although their low cytotoxic effect (CC50 ranged between 0.58 mg/mL and 12.00 mg/mL), the essential oils did not show antiviral activity against coxsakievirus B3.ConclusionThe essential oils obtained from Hypericum triquetrifolium can be used as antimicrobial agents and could be safe at non cytotoxic doses. As shown for the tested essential oils, comparative analysis need to be undertaken to better characterize also the antimicrobial activities of Hypericum triquetrifolium extracts with different solvents as well as their purified fractions and their pure secondary metabolites.

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Section: Discussionmentioning

confidence: 99%

“…The antibacterial activity of H. triquetrifolium was previously reported only against Bacillus brevis , Bacillus cereus , Escherichia coli PBR 322 , Escherichia coli PUC 9 , Pseudomonas aeruginosa and Staphylococcus aureus [51]. However, the antimicrobial activity are generally influenced by the type of assay used [55].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the cytotoxic effect and antibacterial, antifungal, and antiviral activities of Hypericum triquetrifolium Turra essential oils from Tunisia

Rouis

Abid

Koudja

et al. 2013

BMC Complement Altern Med

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“…Hypericum perforatum L. or St. John's wort (Clusiaceae) is a perennial rhizomatous herb traditionally used in herbal medicine throughout the world. Although various activities of H. perforatum extracts have been reported such as antibacterial, antiviral, wound healing, antioxidant, antimicrobial, anti-inflammatory, antinociceptive, antitumor, antiangiogenic, and immunomodulatory activity [1][2][3][4][5][6][7][8][9][10][11], the focus of interest is on its potential as an herbal antidepressant [2]. Flora Croatica Database (FCD) [12] describes two subspecies of H. perforatum in Croatia: ssp.…”

Section: Introductionmentioning

confidence: 99%

Chemical Composition and New Biological Activities of Essential Oil and Hydrosol of Hypericum perforatum L. ssp. veronense (Schrank) H. Lindb

Vuko

Dunkić

Ruščić

et al. 2021

Plants

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The chemical profile, antiproliferative, antioxidant and antiphytoviral activities of the species Hypericum perforatum ssp. veronense (Schrank) H. Lindb. (Clusiaceae) were investigated. Free volatiles were isolated and the chemical composition was determined in the lipophilic fraction (essential oil) and for the first time in the water fraction (hydrosol). The aim is to provide phytochemical data for H. perforatum ssp. veronense useful for distinguishing ssp. veronense from ssp. angustifolium, as there are taxonomic disagreements between them and the composition of the secretory products may be helpful in this respect. In the essential oil, the most abundant compounds identified were α-pinene and n-nonane, while in the hydrosol, myrtenol, carvacrol and α-pinene were the most abundant. Overall, the class of monoterpenes and oxygenated monoterpenes dominated in the EO and hydrosol samples. The essential oil showed high antioxidant activity, in contrast to the antiproliferative activity, where the hydrosol showed exceptional activity against three cancer cell lines: Hela (cervical cancer cell line), HCT116 (human colon cancer cell line) and U2OS (human osteosarcoma cell line). Both the essential oil and hydrosol showed antiphytoviral activity against tobacco mosaic virus infection on the local host plants. This is the first report dealing with biological activities of hydrosol of H. perforatum ssp. veronense, and the obtained results suggest that this traditional medicinal plant is a valuable source of volatiles with promising antiproliferative, antioxidant and antiphytoviral activities.

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“…The antibacterial activity results of H.adenotrichum root (0.156 mg/mL) essential oil against S. aureus is close to the standard compounds (Ampicillin and Clarithromycin). In a prior study, Gudzic et al reported that the essential oil from H. maculatum Crantz in Serbia exhibited a wide range of antibacterial effects (12-16 µL/mL), particularly against S.aureus, E. coli, P. aeruginosa, S. enteritidis, K. pneumoniae, and B. subtilis [36]. Kizil et al investigated the antimicrobial activity of the essential oils of H. scabrum L., H. scabroides, and H. triquetrifolium Turra against the test organisms and a yeast [37].…”

Section: Resultsmentioning

confidence: 99%

Chemical Profiling and Antimicrobial Activity of Essential Oils from Hypericum adenotrichum Spach. An Endemic Species

Saltan¹,

Köse²,

Kırcı³

et al. 2023

jrp

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The purpose of this study was to determine the content of essential oils isolated from the herba and roots of Hypericum adenotrichum Spach., an endemic, wild-growing species of Turkish flora. Gas Chromatography-Mass Spectroscopy (GC-MS) and Gas Chromatography-Flame Ionization Detector (GC-FID) were used to examine the essential oils (EO). In the essential oils of the root of H. adenotrichum, the compounds were found, with undecane (64.4%), hexadecanoic acid (5.3%), and α -copaene (3.9%) as the primary components. Three significant herba compounds, germacrene D (13.3%), hexadecanoic acid (11.3%), and cadinene (6%) were found. Moreover, in this study antimicrobial effects of EO of endemic H. adenotrichum against Escherichia coli NRRL B-3008, Staphylococcus aureus ATCC 6538, Salmonella tymphirium ATCC 14028, Staphylococcus aureus ATCC 700699, Candida albicans ATCC 90028 and Candida krusei ATTC 6258. H. adenotrichum root and herba extracts were made, and LC-MS/MS analysis was used to determine the primary constituents of the extracts. The chemicals found in the herb and root, respectively, include 3-caffeoylquinic acid, 5-caffeoylquinic acid, quercetin hexoside, quinic acid, quercetin, and catechine.

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Composition and antimicrobial activity of the essential oil of Hypericum maculatum Crantz

Cited by 50 publications

References 4 publications

Evaluation of the cytotoxic effect and antibacterial, antifungal, and antiviral activities of Hypericum triquetrifolium Turra essential oils from Tunisia

Evaluation of the cytotoxic effect and antibacterial, antifungal, and antiviral activities of Hypericum triquetrifolium Turra essential oils from Tunisia

Chemical Composition and New Biological Activities of Essential Oil and Hydrosol of Hypericum perforatum L. ssp. veronense (Schrank) H. Lindb

Chemical Profiling and Antimicrobial Activity of Essential Oils from Hypericum adenotrichum Spach. An Endemic Species

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