Composites of Multiwalled Carbon Nanotubes and Molecularly Imprinted Polymers for Dopamine Recognition

Abstract

A novel composite of multiwalled carbon nanotubes (MWNTs) and molecularly imprinted polymers (MIPs) was prepared by using dopamine (DA) as a template molecule. Selective copolymerization of methacrylic acid and trimethylolpropane trimethacrylate (copoly(MAA-co-TRIM)) in the presence of DA was achieved at the vinyl group functionalized MWNT surface. Vinyl groups modified on MWNTs surface are a key factor for the formation the composite of MWNTs-MIPs. Attenuated total reflection Fourier transform infrared spectroscopy, transmission electron microscopy, scanning electron microscopy, and thermogravimetric analysis were used to characterize the composite structure and determine the grafted MIPs quantities in the composite. The properties such as adsorption dynamics, special binding, and selective recognition capacity were evaluated. The results demonstrated that MWNTs-MIPs not only possessed a rapid dynamic adsorption but also exhibited a high selectivity toward DA, compared to epinephrine. The electrochemical sensor fabricated by modifying MWNTs-MIPs on the glassy carbon electrode could recognize DA from ascorbic acids (AA), indicating DA could be detected in the presence of AA. And the modified electrode was used to detect the concentration of DA with a linear range of 5.0 × 10 -7 to 2.0 × 10 -4 mol/L.

Chemical sensors based on polymer composites with carbon nanotubes and graphene: the role of the polymer

“…However, the cases of determining dopamine in ref. 177 and 225 show several similarities. In both cases a GCE modied with a molecularly imprinted MMA-based copolymer was employed to detect dopamine.…”

“…To overcome these problems, many approaches have been established to develop surface molecularly imprinting techniques, particularly for systems incorporating CNTs because of their unique properties, including their remarkable electrical, chemical, mechanical, and structural properties. MIP-CNT composites have been used in several elds such as clinic assays, 172-176 pharmaceutical [177][178][179][180][181] or environmental analysis.…”

Carbon Nanotubes – Imprinted Polymers: Hybrid Materials for Analytical Applications

“…A different MWNTs-MIPs composites was prepared by using dopamine as a template molecule by the selective copolymerization of methacrylic acid and trimethylolpropane trimethacrylate in the presence of the template and vinyl group functionalized MWNT surface (Kan et al, 2008b). In this work, for grafting MIPs on MWNTs, the vinyl group was first introduced on the surface of MWNTs, which directed the selective polymerization of functional monomers and cross linkers in the presence of DA on the MWNTs surface.…”

Sensitive Electrochemical Detection of Dopamine With a Nitrogen-doped Graphene Modified Glassy Carbon Electrode

“…[18] Kan et al applied a multi-walled carbon nanotube composite with homogeneous molecularly imprinted polymers outer layer modified glassy carbon electrode (GCE) for the recognization of DA in presence of ascorbic acid (AA). [19] Oztekin et al used a copper nanoparticles (CuNP) modified GCE for the selective determination of DA in the presence of AA, uric acid and p-acetamidophenol. [20] Niu et al applied a 3,4,9,10-perylene tetracarboxylic acid functionalized GR sheets/multi-walled carbon nanotubes/ionic liquid modified electrode for the DA detection.…”