Composite IS1-tetracycline resistance elements in aerobactin-encoding FIme plasmids from epidemic Salmonella wien

Abstract

Class B tetracycline resistance determinants have been identified in two aerobactin-encoding FIme plasmids representative of those isolated from epidemic Salmonella wien. Genetic data, restriction enzyme analysis of recombinant and mutant plasmids, and Southern blot hybridizations indicate that in both plasmids the class B determinant so far found and described only on Tn10-like transposons is part of a different genetic element. This composite insertion sequence element is about 7 kilobases long and has copies of insertion sequence IS1 at the ends.

Plasmid profiles of Shigella dysenteriae type 1 isolates from Ethiopia with special reference to R-plasmids

“…Casalino et a1. 25 reported the existence of natural derivatives of inc FI,, plasmids of 70-80 Mda. The authors classified these atypical strains as Inc FI,, despite their compatibility with MP10.…”

Molecular analysis of tetracycline resistance in Salmonella enterica subsp. enterica serovars Typhimurium, Enteritidis, Dublin, Choleraesuis, Hadar and Saintpaul: construction and application of specific gene probes

“…1993 ) or Salm. Wien ( Casalino et al . 1988 ), or isolates obtained from infections in humans ( Kariuki et al .…”