Composite based on poly(acrylic acid‐<i>co</i>‐itaconic acid) hydrogel with antibacterial performance

Carrillo-Rodríguez, J.C.; Meléndez‐Ortiz, H. Iván; Puente-Urbina, Bertha; Padron, Gabriela Contreras; Ledezma, Antonio; Betancourt‐Galindo, Rebeca

doi:10.1002/pc.23917

Cited by 23 publications

(9 citation statements)

References 35 publications

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“…The minimum bacterial concentration was done by disk diffusion method by using PMMA, NiO NPs, and polymer nanobiocomposites (0.2, 0.6, and 1%) on fresh cultures of M. luteus, S. epidermidis, Y. enterocolitica, and K. pneumoniae . After 24 h, bacterial broth cultures were streaking into agar plate to determine their minimum bactericidal inhibition and different concentration of polymer composite (0.2, 0.6, and 1%) and NPs were loaded on sterile disk and tested their MBC against gram negative bacteria , such as Y. enterocolitica and K. pneumoniae as shown in Fig. .…”

Section: Resultsmentioning

confidence: 99%

In vitro cytotoxic effect of spikenard herbal immobilized polymer nano‐biocomposites: Toward bioinspired antimicrobial agent

Priya¹,

Jeyajothi²

2018

Polymer Composites

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We report the intrinsic biological properties of nickel oxide nanoparticle (NiO NPs) encapsulated Nardostachys jatamansi DC-based polymethyl methacrylate (PMMA) via free radical polymerization technique. A simple and cost effective NiO NPs was adapted to synthesize via sol-gel/co-precipitation method to afford crystalline structures of NPs and it was confirmed by X-ray diffraction (XRD) patterns (2θ at 38.78 [111] and 62.66 [220]). The results demonstrated that the sparingly loaded NiO NPs onto composites exhibited the lowest crystallinity, which led to better dispersion into the polymer matrix and also observed by scanning electron microscopy (SEM) and atomic force microscopy (AFM). ATR-IR enunciate the functional groups of polymer nano-biocomposites attributed at 1730 cm −1 ( C=O), 1446 cm −1 ( CH 3 -asymmetric deformation), 1162 cm −1 ( C-N), and 822 cm −1 ( C-H), which were found to be good agreement for the formation of polymer composites and further confirmed their structural identification by NMR, fluorescence spectroscopy and UV-vis spectroscopy. This hybrid nano-biocomposite has been utilized for antimicrobial studies using a gram positive and gram-negative bacteria and showed better results on minimum bactericidal concentration (MBC) assay against Micrococcus luteus, Staphylococcus epidermidis, Yersinia enterocolitica, and Klebsiella pneumoniae. In addition, cell morphology and proliferation were monitored by fluorescence microscopy. The MTT assay results showed that the nano-biocomposites possessed significantly low cytotoxicity against human keratinocyte cell lines (HaCaT).

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Section: Resultsmentioning

confidence: 99%

In vitro cytotoxic effect of spikenard herbal immobilized polymer nano‐biocomposites: Toward bioinspired antimicrobial agent

Priya¹,

Jeyajothi²

2018

Polymer Composites

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“…The NaCMC‐HPMC‐ZnO hydrogel films (5 cm × 5 cm) were immersed in PBS, pH 7.4 at 37°C for 24 h. The swollen films were weighed after removing the excess surface water and the swelling degree (Mean ± Std. Dev) was calculated as defined below:

SD (() %) = ((), W_{s} - W_{d}) / W_{d} \times 100

where W s and W d are the weights of swollen and dried hydrogel films, respectively.…”

Section: Methodsmentioning

confidence: 99%

“…Besides, they absorb large amounts of water or biological fluids thereby preventing maceration while permitting the transport of nutrients, oxygen, and metabolic products. These characteristics make hydrogels an excellent candidate for various biomedical applications, especially as a component in wound healing materials . Among several polymers of cellulose derivatives, sodium carboxymethylcellulose (NaCMC) and hydroxypropylmethylcellulose (HPMC) have been widely investigated to fabricate hydrogels for wound healing applications .…”

Section: Introductionmentioning

confidence: 99%

“…Among inorganic materials, zinc oxide (ZnO) has attracted significant interest due to its heat stability, antimicrobial action, less toxicity, and UV‐blocking properties . The antimicrobial activity of ZnO against Staphylococcus aureus , Escherichia coli , Pseudomonas aeruginosa , Bacillus subtilis , Bacillus megaterium , Sarcina lutea , Klebsiella pneumonia , Candida albicans , Pseudomonas vulgaris , and Aspergillus niger was reported in earlier literature . Furthermore, Zn 2+ is an essential element for cell proliferation.…”

Section: Introductionmentioning

confidence: 99%

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Formation and characterization of zinc oxide complexes in composite hydrogel films for potential wound healing applications

et al. 2020

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The objective of this investigation is to fabricate hydrogel films comprising sodium carboxymethylcellulose and hydroxypropylmethylcellulose in the presence of citric acid (CA) and zinc oxide nanoparticles (ZnO NPs) by solution casting method. X‐ray diffraction patterns showed that the crystallinity of films decreases and also ZnO crystalline peaks were disappeared with increase in CA concentrations (5‐20 wt%). Fourier transform infrared and micro‐Raman analysis confirmed the absence of Zn‐O vibration. It was found that swelling degree, tensile strength, and initial decomposition temperature of the films decreased with increase in CA. As CA concentration increases, the agglomeration of the NP increases according to field emission scanning electron microscopy and field emission transmission electron microscopy (FETEM) analysis. FETEM‐EDX elemental mapping showed that the NP is composed of C, O, and Zn. The prepared films released zinc and showed significant antibacterial activity against Escherichia coli MTCC 1610 and Staphylococcus aureus MTCC 6538. The fabricated films exhibited biocompatibility with HaCaT cells. The analysis reports that the prepared hydrogel films may be used for potential wound healing applications.

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“…Polymer microgels have attained much attention due to their unique physical and chemical properties along with their responsive nature to different environmental stimuli like temperature, pH and ionic strength of the medium . Microgels are widely used in sensing , drug delivery , emulsion stabilization , separation processing , environmental pollutants adsorption , nanotechnology and catalysis . The use of microgels as microreactor for the preparation of noble metal nanoparticles was first reported by Antonietti et al .…”

Section: Introductionmentioning

confidence: 99%

Platinum nanoparticles fabricated multiresponsive microgel composites: Synthesis, characterization, and applications

2016

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This tutorial review describes the recent research progress of platinum nanoparticles fabricated composite microgels. Synthetic methods, characterization and applications of platinum nanoparticles loaded composite polymer microgels have been elaborated. Different types of platinum nanoparticles loaded hybrid microgel systems on the basis of their morphology have also been discussed in detail. Stability of platinum nanoparticles inside different microgel systems reported in literature has been described. Applications of platinum nanoparticles loaded composite microgels in the field of catalysis are mainly discussed in this review. An overview of catalytic applications of platinum nanoparticles fabricated hybrid microgels has been provided here along with future perspectives of this area.

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Composite based on poly(acrylic acid‐co‐itaconic acid) hydrogel with antibacterial performance

Cited by 23 publications

References 35 publications

In vitro cytotoxic effect of spikenard herbal immobilized polymer nano‐biocomposites: Toward bioinspired antimicrobial agent

In vitro cytotoxic effect of spikenard herbal immobilized polymer nano‐biocomposites: Toward bioinspired antimicrobial agent

Formation and characterization of zinc oxide complexes in composite hydrogel films for potential wound healing applications

Platinum nanoparticles fabricated multiresponsive microgel composites: Synthesis, characterization, and applications

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