Composite aqueous microgels: an overview of recent advances in synthesis, characterization and application

Pich, Andrij; Adler, Hans‐Juergen P.

doi:10.1002/pi.2142

Cited by 104 publications

(62 citation statements)

References 213 publications

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“…Electronic mail: pich@dwi.rwth-aachen.de microgels with their unique properties can enhance. Recently, numerous reports on the nanogel/microgel synthesis, 10 characterization, 11-13 modification 14,15 and application in drug delivery, 16,17 design of biomaterials, 18 development of sensors 19 are emerging, thereby illustrating the potential of the crosslinked polymer colloids in a wide range of applications (and fundamental research).…”

Section: Introductionmentioning

confidence: 99%

“…Different approaches to incorporate nanoparticles into aqueous nanogels and microgels were recently reviewed. 15,40 A large variety of nanoparticles have been incorporated into microgels, including NPs of conducting polymers, 41,42 The incorporation of different nanomaterials into microgel particles is a topic under intense study. There are three profoundly distinct approaches for incorporating NPs into microgels: (1) The first utilizes the microgel as a template for in-situ preparation of nanoscale materials such as inorganic NPs.…”

Section: Introductionmentioning

confidence: 99%

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Synthesis of hybrid microgels by coupling of laser ablation and polymerization in aqueous medium

Nachev

Zand

Coger

et al. 2012

Journal of Laser Applications

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Loading microgels with bioactive nanoparticles (NPs) often requires multiple synthesis and purification steps, and organic solvents or precursors that are difficult to remove from the gel. Hence, a fast and aqueous synthesis procedure would facilitate the synthesis of inorganic–organic hybrid microgels. Two microgel compounds were hybridized with laser-generated zinc oxide (ZnO) NPs prepared in a single-step procedure. ZnO NPs were formed by laser ablation in liquid, while the polymer microgels were synthesized in-situ inside the ablation chamber. Further, the authors report the preparation of two different microgel systems. The first one was produced without the use of chemical initiator forming hydrogels with ZnO NPs and diffuse morpholgy. Typical microgel colloids were also synthesized via a conventional chemical method in a preheated reaction chamber. The existence of microgel colloids partially loaded with ZnO NPs was confirmed in a transmission electron microscopy investigation. Fourier transform infrared spectroscopic measurements and dynamic light scattering verify the formation of polymer colloids. These initial results indicate the application potential of laser ablation in microgel precursor solution for the fabrication of polymeric carriers for inorganic nanoparticles. Preliminary biological tests using zinc chloride demonstrated negative dose effects on primary cell culture with zinc concentrations above 200 μM but no noticeable influence at 100 μM.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Synthesis of hybrid microgels by coupling of laser ablation and polymerization in aqueous medium

Nachev

Zand

Coger

et al. 2012

Journal of Laser Applications

View full text Add to dashboard Cite

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“…However, uniformly dispersing colloids in polymer matrices, and vice versa, has represented a challenge that requires careful tuning of the interactions and the processing conditions [5][6][7] . Nature, on the other hand, can assemble to perfection complex composite materials for a variety of functions.…”

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confidence: 99%

Blood-clotting-inspired reversible polymer–colloid composite assembly in flow

et al. 2013

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Blood clotting is a process by which a haemostatic plug is assembled at the site of injury. The formation of such a plug, which is essentially a (bio)polymer-colloid composite, is believed to be driven by shear flow in its initial phase, and contrary to our intuition, its assembly is enhanced under stronger flowing conditions. Here, inspired by blood clotting, we show that polymer-colloid composite assembly in shear flow is a universal process that can be tailored to obtain different types of aggregates including loose and dense aggregates, as well as hydrodynamically induced 'log'-type aggregates. The process is highly controllable and reversible, depending mostly on the shear rate and the strength of the polymer-colloid binding potential. Our results have important implications for the assembly of polymercolloid composites, an important challenge of immense technological relevance. Furthermore, flow-driven reversible composite formation represents a new paradigm in non-equilibrium self-assembly.

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“…9,10 Hybrid materials can be prepared by combining such microgels with inorganic nanoparticles to create multifunctional particles. [11][12][13][14] Ideally these hybrid materials combine the responsiveness of the microgel with the optical, catalytic or magnetic properties of the embedded inorganic material. Many hybrid materials are based on the polymer coating of preformed nanoparticles [15][16][17] or the in situ synthesis of inorganic nanoparticles within a polymer matrix.…”

Section: Introductionmentioning

confidence: 99%

Interaction of gold nanoparticles with thermoresponsive microgels: influence of the cross-linker density on optical properties

Gawlitza

Turner

Polzer

et al. 2013

Phys. Chem. Chem. Phys.

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The interaction of spherical gold nanoparticles (Au-NPs) with microgels composed of chemically crosslinked poly-(N-isopropylacrylamide) is reported. Simple mixing of the two components leads to adsorption of the gold particles onto the microgels. Different loading densities can be achieved by varying the ratio of gold particles to microgel particles. The adsorption of gold nanoparticles is analysed by TEM, UV-Vis absorption spectroscopy and SAXS. The influence of the microgel mesh size on the adsorption of gold nanoparticles is investigated by using microgels with three different cross-linker densities. The results suggest a strong relationship between the nanoparticle penetration depth and the cross-linker density. This, in turn, directly influences the optical properties of the colloids due to plasmon resonance coupling. In addition, information about the mesh size distribution of the microgels is obtained. For the first time the change in optical properties by varying cross-linker density and temperature is directly related to the formation of dimers of gold particles, proven by SAXS.

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Composite aqueous microgels: an overview of recent advances in synthesis, characterization and application

Cited by 104 publications

References 213 publications

Synthesis of hybrid microgels by coupling of laser ablation and polymerization in aqueous medium

Synthesis of hybrid microgels by coupling of laser ablation and polymerization in aqueous medium

Blood-clotting-inspired reversible polymer–colloid composite assembly in flow

Interaction of gold nanoparticles with thermoresponsive microgels: influence of the cross-linker density on optical properties

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