Components of the Complete Blood Count as a Risk Predictor for Incident Hypertension in a Large Taiwanese Population Follow-up Study

Abstract

CVD and death. 6,7 However, nearly all elements of the complete blood count (CBC), including WBCs, red blood cells (RBCs), and platelets, are also involved in the underlying pathogenesis of atherosclerosis. 8-10 The relationship between arterial calcification and RBCs is bidirectional: calcification promotes hemorrhage, and hemoglobin (Hb) release promotes calcification of elastic vascular tissues. 9Local RBC hemolysis has also been associated with both early and advanced stages of atherosclerosis. 9 In addition to their known functions in thrombosis and hemostasis, platelets provide a link among inflammation, thrombosis, and atherosclerosis. 10 In atherosclerosis, platelets promote the recruitment of inflammatory cells to the lesion site and release large amounts of inflammatory mediators by interacting with endothelial cells and circulating leukocytes. 10 Various elements of the CBC have been associated with H ypertension (HT) is one of the most common diseases and an important cause of cardiovascular disease (CVD) and death in developed countries. 1,2 It causes cardiac hypertrophy, which leads to cardiomyopathy and heart failure, as well as serious blood vessel-related complications, such as stroke, coronary artery disease, aortic aneurysm, aortic vascular dissection, and renal vascular disease, all of which can result in permanent damage and death. 3 The prevalence of HT among adults aged ≥18 years in Taiwan is approximately 25%, and the rate continues to increase. 4 HT is a multifactorial disease, and inflammation is known to play an important role in the development of both atherosclerosis and HT. 5 An elevated circulating white blood cell (WBC) count, a well-known independent marker of systemic inflammation, has been associated with

The association between red cell distribution width and newly diagnosed hypertension among adults in Northern Sudan: a case-control study

“…Among non-communicable diseases, hypertension is considered the leading risk factor of death globally [ 1 ]. Various predictors of hypertension have been reported, including complete blood count (CBC) parameters such as red cell distribution width (RDW) [ 4 , 5 ].…”