Components of Root Bark ofCudrania tricuspidata2. Structures of Two New Isoprenylated Flavones, Cudraflavones A and B.

Abstract

Two new isoprenylated flavones, cudraflavones A and B were isolated from the root bark of CUDRANIA TRICUSPIDATA (Carr.) Bur. (Japanese name "Hariguwa", Moraceae). The structures of cudraflavones A and B were shown to be 1 and 2, respectively, on the basis of spectral data. Photo-oxidative cyclization occurred with cudraflavone B leading to the formation of a hydroperoxide possessing a dihydrooxepin ring.

Hepatoprotective Compounds of the Roots of Cudrania tricuspidata on Tacrine-Induced Cytotoxicity in Hep G2 Cells

“…The structures of isolated compounds were identified as euchrestaflavanone C (1), 9) gerontoxanthone A (2), 10) cudraxanthone B (3), 11) cudraflavone B (4), 12) gericudranin E (5), 13) cudraxanthone C (7), 11) and cudraxanthone H (8), 14) respectively, by comparing UV, (Table 1), including one carbonyl group, two aromatic rings with six oxygenated carbons, and two C 5 groups, corresponding to a diprenylated and tetrahydroxylated xanthone. The positions of the substituents on the ring system were determined on the basis of HMBC correlations, as shown in Table 1.…”

Novel Prenylated Xanthones from Garcinia gerrardii HARVEY

“…The 1,l-dimethylallyl side chain was identified by comparison with published data [13]. A quaternary C-atom at 69.6 ppm in conjunction with two vicinal secondary OH groups and two CH, groups suggested a 3,4-dihydroxy-2,2-dimethylchroman moiety.…”

Phenolic Compounds of the Mulberry Tree and Related Plants

“…+160° Kuwanon H (26) -536° kuwanon R (149) +56° Kuwanon K (153) -218° kuwanon V (150) +145° Kuwanon L (154) -277° cha1collloracin (103) +193° Kuwanon N (155) -188° KuwanonO (156) -243° Kuwanon P (158) -509° Kuwanon W (157) The absolute configuration of the chiral centers on the cyclohexene ring of kuwanon L (154) (133) was confirmed by the following results (152).…”