Component analysis and anti-pulmonary fibrosis effects of Rosa sterilis juice

Abstract

Rosa sterilis is a new variety of Rosa roxburghii Tratt, and is rich in bioactive substances, but its role in pulmonary fibrosis has not been elucidated. The purpose of this...

Role of extracted phytochemicals from Rosa sterilis S. D. Shi in DSS-induced colitis mice: potential amelioration of UC

“…38 Surprisingly, WRS also inhibited the mRNA expression of inflammatory mediators, especially on IL-6 and COX-2 ( p < 0.01). This may be attributed to the high content of vitamin C and SOD in R. sterilis fruits, 11 both of which can help reduce the production of inflammatory mediators by reducing oxidative stress and neutralizing free radicals. 39…”

“…14 Nevertheless, the biological function of RS has not been fully studied. Wang et al found that RS juice could inhibit TGF-β1-induced epithelial–mesenchymal transition and fibroblast differentiation; 11 Zhu et al demonstrated that R. sterilis flavonoids showed strong α-glucosidase inhibitory activity in vitro . 15…”

“…10 RS is a unique resource in Anshun, Guizhou Province, and its annual output has reached 100 000 tons. 11 Some studies have compared the chemical substance and nutrient composition of RS and RRT. 12 Liu et al 13 performed a comprehensive analysis of RS and RRT.…”

“…14 Nevertheless, the biological function of RS has not been fully studied. Wang et al found that RS juice could inhibit TGF-β1-induced epithelialmesenchymal transition and fibroblast differentiation; 11 Zhu et al demonstrated that R. sterilis flavonoids showed strong α-glucosidase inhibitory activity in vitro. 15 Non-targeted analytical technology is an analytical method that detects unknown compounds in samples without knowledge of the sample compounds, including chromatography, mass spectrometry and spectroscopy.…”

Efficient Extraction and Mechanism Analysis of Different Polarity Phytochemicals from Rosa roxburghii by a Green CO2-Responsive Switchable Solvent Combined with Ultrasound

“…This fruit has traditionally been used as a food and herbal medicine for certain diseases such as diarrhea, hyperlipidemia, and enteritis . Current research indicates that Rosa roxburghii juice has antipulmonary fibrosis effects . In addition, the Rosa roxburghii fruit has been found to have antioxidant, antidiabetic, antimutagenic, antiatherosclerotic, antitumor, and radiation protection activities. , By 2020, the Rosa roxburghii planting area in Guizhou Province expanded to 133,300 ha, and the output of Rosa roxburghii fruits and related products reached 100 tons and 26,200 tons, respectively.…”