Complications Related to the Pressor Response to Endotracheal

Fox, Elisabeth J.; Sklar, Garry S.; Hill, Constance H.; Villanueva, Raymond; King, Benton D.

doi:10.1097/00132586-197810000-00021

Cited by 2 publications

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“…Laryngoscopy is a well-known cause of extreme transient reflex hypertension in all individuals. The problem is aggravated in eclamptic women50 51 and may be so extreme as to cause acute pulmonary oedema 52…”

Section: Principles Of Treatment Of Eclampsiamentioning

confidence: 99%

Modern management of eclampsia

Salha

Walker

1999

Postgraduate Medical Journal

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SummaryEclampsia, the occurrence of a seizure in association with preeclampsia, remains an important cause of maternal mortality and morbidity. Despite being recognised since antiquity, consistent management practices are still lacking. Given that the aim of good care is to prevent seizures, it is disappointing that in the majority of cases the first eclamptic convulsion occurs after admission to hospital. This indicates that either the women who are likely to have a convulsion were not identified accurately, or the treatment given was ineVective. The answer to poor management of eclampsia lies in better education and training of all obstetricians, anaesthetists, midwives, and general practitioners in the diagnosis and treatment of severe pre-eclampsia and eclampsia. Protocols for the management of fluid balance, antihypertensive and anticonvulsant therapies should be available and reviewed regularly. The universal adoption of such guidelines in all obstetric units would substantially reduce elements of substandard care which have repeatedly been identified in the triennial reports of the confidential enquiries into maternal deaths in the UK.

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Section: Principles Of Treatment Of Eclampsiamentioning

confidence: 99%

Modern management of eclampsia

Salha

Walker

1999

Postgraduate Medical Journal

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Topical anesthesia of tracheal receptors

Camporesi¹,

Mortola²,

Sant'Ambrogio³

et al. 1979

Journal of Applied Physiology

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Two types of sensory receptors were individually identified in dogs on the exposed mucosa of the extrathoracic trachea: slowly adapting stretch receptors (SAR) and rapidly adapting receptors (RAR). Increasing concentrations of lidocaine (L), bupivacaine (B), and tetracaine (T) solutions were topically applied on the mucosa over the sensory fields of the receptors, while their neural activity in response to an appropriate stimulus was recorded. Action potentials from SARS were blocked by the anesthetic at a much higher concentration and with larger exposure times than potentials evoked from RARs (mean values: L = 51.1 mM for 7.4 min and 1.48 mM for 1.03 min, respectively; B = 9.4 mM for 9.4 min and 0.13 mM for 0.23 min; and T = 4.9 mM for 9.8 min and 0.06 mM for 2 min). The minimal blocking concentration of the topical anesthetics varied widely (L = 20 times, B = 5, and T = 5) among SARs and less (L = 3.2, B = 2, and T = 4) among RARs. These results could be explained by a different location in the mucosa of the two types of receptors and suggest the feasibility of a differential blockade by topical anesthetics.

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Complications Related to the Pressor Response to Endotracheal

Cited by 2 publications

References 0 publications

Modern management of eclampsia

Modern management of eclampsia

Topical anesthesia of tracheal receptors

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