Complications related to fracture treatment in HIV patients

Randelli, Filippo; Pulici, Luca; Favilla, Sara; Maglione, Daniela; Zaolino, Carlo; Carminati, S.; Pace, Fabrizio; Randelli, Pietro

doi:10.1016/j.injury.2013.09.026

Cited by 4 publications

(6 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Lukhele et al reported a case of late implant sepsis at 4 years in a seropositive patient who had previously undergone spine stabilization surgery. Furthermore, Randelli et al [8] presented a case report of a 40-year-old woman who was HIV-positive and developed an infection 2 years after undergoing endomedullary nailing for a femoral pertrochanteric fracture. Phaff et al [19], in a study of 14 HIVpositive patients, found one patient had metal removed for sepsis and one patient had a nonunion.…”

Section: Discussionmentioning

confidence: 99%

“…Brijlall [4] later described a number of such cases, warning that this had the potential to alter clinical practice in relation to selection of patients for internal fracture fixation, and suggesting that removal of all such implants in HIV-positive individuals should be considered. This feeling was echoed by numerous other study groups [5][6][7][8][9]. Even this year, Randelli also called for removal of all implants in HIV positive patients [6].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Late implant sepsis after fracture surgery in HIV positive patients

Graham

Bates

Mkandawire

et al. 2015

Injury

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Late implant sepsis after fracture surgery in HIV positive patients

Graham

Bates

Mkandawire

et al. 2015

Injury

View full text Add to dashboard Cite

“…3 HIV-positive subjects may encounter opportunistic infections and malignancies, because of cellular immunological, humoral and non-specific deficiencies. 4 , 5 At the same time, highly active antiretroviral therapy, which has been widely used and transformed HIV infection to a chronic, manageable condition, results in the increase of life expectancy of HIV/AIDS patients as well as the number of HIV-positive patients undergoing orthopaedic surgeries. 1 …”

Section: Introductionmentioning

confidence: 99%

“…Li also advocates that the wound in HIV positive patients can be normally healed and no infection occur in most of patients. 3 In addition, some authors suggest that implant sepsis may occur after internal fixation, demonstrating that removal of implants in HIV-positive individuals should be considered, 5 , 8 but in another study of 91 HIV-positive patients, Graham concluded that it was safe to perform internal fixation and no increased risk of implant sepsis was detected. 9 Apparently, controversies are common.…”

Section: Introductionmentioning

confidence: 99%

Analysis of the surgical treatment of fracture in HIV positive patients: A clinical study

Zhao²,

Sun³

et al. 2017

Pak J Med Sci

View full text Add to dashboard Cite

Objective:To evaluate the incidence of postoperative infection and fracture nonunion as well as the risk factors for postoperative infection in human immunodeficiency virus (HIV) positive patients.Methods:From May 2013 to March 2016, the HIV positive fracture patients treated surgically in orthopaedics department of our hospital were analyzed retrospectively, and fifty HIV negative fracture patients during the same period were selected as control. The clinical data of included patients were reviewed. The incidence of postoperative infection and fracture nonunion were compared between the two groups, and the risk factors for postoperative infection in HIV positive patients were evaluated.Results:The incidence of poor wound healing and incision infection in HIV positive group was higher than that in HIV negative group, but there were no significant differences between the two groups (p>0.05). Multivariable regression analysis demonstrated that HIV clinical category (p<0.05), CD4+T-lymphocyte category (p<0.01) and open fracture (p<0.05) were independent risk factors for postoperative wound infections, but age, gender, operation time, incision type, emergency operation, albumin and lymphocyte count were not (p>0.05). There was no significant difference in the rate of nonunion between the two groups (p>0.05).Conclusion:The incision can be healed, and fracture can be united normally in most of HIV positive patients with fracture, and postoperative wound infections were significantly associated with HIV clinical category, CD4+T-lymphocyte category and open fracture.

show abstract

“…Results of studies examining the safety and long-term implications of surgical interventions in HIV patients have been varied (Horberg et al, 2006). Some studies have demonstrated little difference in surgical healing and outcomes compared to people not living with HIV, while others have suggested that PLHIV are more likely to experience delayed healing and postoperative complications (Randelli et al, 2014; Richardson et al, 2008; Triant, Brown, Lee, & Grinspoon, 2008). Furthermore, evidence suggests that successful healing after surgical interventions may be related to how well an individual’s HIV is controlled at the time of surgery, with more complications experienced by individuals who are more immunocompromised compared to those who are virally suppressed (Horberg et al, 2006; Richardson et al, 2008).…”

Section: Increased Risk For Delayed or Complicated Healingmentioning

confidence: 99%

People Living With HIV: Implications for Rehabilitation Nurses

Perazzo¹,

Webel²,

McGough³

et al. 2018

Rehabilitation Nursing

View full text Add to dashboard Cite

Purpose To present a brief overview of challenges faced by people living with HIV (PLHIV) as they age, to discuss the relevance of HIV to rehab nurses, and to provide evidence-based recommendations for rehabilitation professionals working with PLHIV. Design Current Issues Article Methods Literature review related to age-related comorbidities in PLHIV with implications for rehabilitation nurses. Conclusions PLHIV experience higher rates of age-related comorbidities compared to the general population and will require rehabilitation expertise in their healthcare. Understanding unique characteristics of PLHIV as well as applying focused assessment and tailored interventions in PLHIV will give rehabilitation nurses the tools to successfully guide PLHIV through the rehabilitation process and optimize clinical outcomes. Clinical Relevance As people with HIV age and experience acute and chronic comorbidities, they will require the clinical expertise of rehabilitation nurses in the process to successfully transition through acute and sub-acute healthcare and regain function.

show abstract

Complications related to fracture treatment in HIV patients

Cited by 4 publications

References 31 publications

Late implant sepsis after fracture surgery in HIV positive patients

Late implant sepsis after fracture surgery in HIV positive patients

Analysis of the surgical treatment of fracture in HIV positive patients: A clinical study

People Living With HIV: Implications for Rehabilitation Nurses

Contact Info

Product

Resources

About