2023
DOI: 10.1177/20501684231197717
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Complications of toxins and fillers in facial aesthetics

Souphiyeh Samizadeh,
Koenraad De Boulle

Abstract: Dermal filler and botulinum toxin injections are among the most performed non-invasive procedures for rejuvenation and contouring, internationally. Although most dermal fillers and approved botulinum toxins are well tolerated with a high safety profile, adverse events and/or complications can happen. Injection-related sequelae and side effects are usually rare, mild, transient, and self-limiting in nature. However, devastating and life-changing complications, such as intravascular occlusion, skin necrosis, per… Show more

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Cited by 3 publications
(1 citation statement)
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“…Of these ways, using filler materials which may be absorbable or not (Cassuto et al 2021;Mandal and Gama 2021;Safran et al 2021). These materials should be accepted by the US Food and Drug Administration authorities because its use can cause unwanted drawbacks (Wang et al 2021;Samizadeh and De Boulle, 2023). Of these undesirable drawbacks are tissue inflammation, hypersensitivity, ecchymosis, local mass formation, edema, granulomatous reaction, fistulations, abscess formation, tissue necrosis and loss of vision (Shahrabi-Farahani et al 2014;Kassir et al 2020).…”
Section: Discussionmentioning
confidence: 99%
“…Of these ways, using filler materials which may be absorbable or not (Cassuto et al 2021;Mandal and Gama 2021;Safran et al 2021). These materials should be accepted by the US Food and Drug Administration authorities because its use can cause unwanted drawbacks (Wang et al 2021;Samizadeh and De Boulle, 2023). Of these undesirable drawbacks are tissue inflammation, hypersensitivity, ecchymosis, local mass formation, edema, granulomatous reaction, fistulations, abscess formation, tissue necrosis and loss of vision (Shahrabi-Farahani et al 2014;Kassir et al 2020).…”
Section: Discussionmentioning
confidence: 99%