Complications of the treatment of endoscopic biliary strictures developing after liver transplantation

Abstract

Endoscopic maneuvering for biliary dilatation and/or stent placement following OLT was associated with a higher risk of post-ERCP pancreatitis than the use of the same technique for the treatment of malignant biliary stricture. Endoscopic treatment after OLT was a significant risk factor for post-ERCP pancreatitis.

Endoscopic management of biliary strictures after living donor liver transplantation

“…To prolong stent patency and maintain the advantages of DD biliary reconstruction, some Japanese groups have placed PSs completely in the bile duct (inside stents) for post-LDLT biliary complications [18,19,[73][74][75]. Because the distal end of an inside stent is located in the bile duct, duodenobiliary reflux is theoretically prevented.…”

Risk Factors of Post-ERCP Pancreatitis at a Tertiary Referral Center in Japan

“…Previous PEP studies conducted in Japan, including a retrospective study by a small facility, 3 have focused on the posttransplantation risks, 4 the association with accessory pancreatic duct patency 5 and cholangitis, 6 the pancreatic duct guidewire method, 7 pancreatic duct stenting, 8 endoscopic papillary balloon dilation (EPBD), 9 used drugs, 10 and pancreatic duct stent in high-risk patients. 11 Here, we report the first ERCP study that was conducted at a highvolume center in an educational institution in Japan.…”

Endoscopic treatment in biliary strictures after pediatric liver transplantation

“…The most common are pancreatitis with the incidence varying between 2.7 and 12.5%, cholangitis occurring between 3.3 and 7.7% and bleeding after sphincterotomy between 1.6% and 23.5% …”

“…21,22 In adults, biliary sphincterotomy, renal failure, repeated pancreatic injections, and therapy with mTOR inhibitors may place patients at risk of complications after ERCP, whereas steroid therapy might act as a protective factor for the development of post-ERCP complications. 23 The most common are pancreatitis with the incidence varying between 2.7 and 12.5%, 13,[23][24][25] cholangitis occurring between 3.3 and 7.7% 13,23-25 and bleeding after sphincterotomy between 1.6% and 23.5%. 11,[23][24][25] The main limitation of our study is the retrospective nature.…”

“…23 The most common are pancreatitis with the incidence varying between 2.7 and 12.5%, 13,[23][24][25] cholangitis occurring between 3.3 and 7.7% 13,23-25 and bleeding after sphincterotomy between 1.6% and 23.5%. 11,[23][24][25] The main limitation of our study is the retrospective nature.…”