Complications of Radiofrequency Ablation of Neoplasms

Nemcek, Albert A.

doi:10.1055/s-2006-941448

Cited by 36 publications

(37 citation statements)

References 65 publications

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“…Subcapsular hematoma and abdominal wall hematoma have also been described. The first one occurs more often in subcapsular tumors, when tract cauterization is [18,19] . Post procedure imaging is also essential since these complications usually occur in the first hours after the ablation.…”

Section: Hemorrhagic Complicationsmentioning

confidence: 99%

Complications of radiofrequency ablation of hepatic tumors: Frequency and risk factors

Fonseca

Santin

Gomes

et al. 2014

WJH

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Radiofrequency ablation (RFA) has become an important option in the therapy of primary and secondary hepatic tumors. Surgical resection is still the best treatment option, but only a few of these patients are candidates for surgery: multilobar disease, insufficient liver reserve that will lead to liver failure after resection, extra-hepatic disease, proximity to major bile ducts and vessels, and co-morbidities. RFA has a low mortality and morbidity rate and is considered to be safe. Thus, complications occur and vary widely in the literature. Complications are caused by thermal damage, direct needle injury, infection and the patient's co-morbidities. Tumor type, type of approach, number of lesions, tumor localization, underlying hepatic disease, the physician's experience, associated hepatic resection and lesion size have been described as factors significantly associated with complications. The physician in charge should promptly recognize high-risk patients more susceptible to complications, perform a close post procedure follow-up and manage them early and adequately if they occur. We aim to describe complications from RFA of hepatic tumors and their risk factors, as well as a few techniques to avoid them. This way, others can decrease their morbidity rates with better outcomes.

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Section: Hemorrhagic Complicationsmentioning

confidence: 99%

Complications of radiofrequency ablation of hepatic tumors: Frequency and risk factors

Fonseca

Santin

Gomes

et al. 2014

WJH

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“…The second way results in complications relate to the RFA device passed through tissue to a target organ such as bleeding, pneumothorax, and infection. The third way associates with sedation and anesthesia [8]. This study does not focus on procedure-related complications.…”

Section: Discussionmentioning

confidence: 99%

Propofol-Based Deep Sedation for Percutaneous Radiofrequency Ablation in Sick Elderly Patients with Hepatocellular Carcinoma in a Developing Country

2017

JACCOA

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The aim of this study was to evaluate and compare the clinical efficacy of propofol-based deep sedation (PBDS) for percutaneous radiofrequency ablation (RFA) in sick (American Society of Anesthesiologists [ASA] physical status III-IV) and nonsick (ASA physical status I-II) elderly patients in a teaching hospital in Thailand. We undertook a retrospective review of the sedation service records of elderly patients who underwent RFA procedures from 2010 to 2012. Patients were classified into two groups according to ASA physical status. In group A, patients had ASA I-II, while in group B, patients had ASA III-IV. Primary outcome variable was the successful completion of procedure. Secondary outcome variables were sedation-related complications during and immediately after procedure. There were 113 elderly patients who underwent RFA procedures by using PBDS during the study period. Of these, 69 patients were in group A and 44 patients were in group B. There were no significant differences in age, weight, duration of sedation, and mean dose of propofol, fentanyl, and midazolam between the two groups. All procedures in both groups were successfully completed. Overall and cardiorespiratory-related complications in both groups were not significantly different. All sedation-related complications were easily treated, with no adverse sequelae. PBDS for percutaneous RFA in sick elderly patients by trained anesthetic personnel with appropriate monitoring was safe and effective. The clinical efficacy of this technique in sick elderly patients was not different or worse than in nonsick elderly patients. Serious complications were rare.

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“…This natural insulation concentrates thermal energy at the site of the lesion with local air exchange and vascular flow carrying heat energy away from the target ablation zone [32]. Although this 'heat sink' phenomenon can have a protective effect on adjacent vulnerable non-target structures it also limits the effectiveness of RF heating [33]. In addition, RF ablation is limited due to tissue char effects, which impede thermal conductance and can limit thermal necrosis near the periphery of the lesion [34,35].…”

Section: Clinical Outcomesmentioning

confidence: 99%

Clinical experiences with microwave thermal ablation of lung malignancies

Sidoff

Dupuy

2016

International Journal of Hyperthermia

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Approximately 30% of early stage lung cancer patients are not surgical candidates due to medical comorbidities, poor cardiopulmonary function and advanced age. These patients are traditionally offered chemotherapy and radiation, which have shown relatively modest improvements in mortality. For over a decade, percutaneous image-guided ablation has emerged as a safe, cost-effective, minimally invasive treatment alternative for patients who would otherwise not qualify for surgery. Although radiofrequency ablation (RFA) is currently the most extensively studied and widely utilised technique in the treatment of lung malignancies, there is a growing body of evidence that microwave ablation (MWA) has several unique benefits over RFA and cryoablation in the lung. This article reviews our institution's clinical experiences in the treatment of lung malignancies with MWA including patient selection, procedural technique, imaging follow-up, treatment outcomes and comparison of ablation techniques. ARTICLE HISTORY

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Complications of Radiofrequency Ablation of Neoplasms

Cited by 36 publications

References 65 publications

Complications of radiofrequency ablation of hepatic tumors: Frequency and risk factors

Complications of radiofrequency ablation of hepatic tumors: Frequency and risk factors

Propofol-Based Deep Sedation for Percutaneous Radiofrequency Ablation in Sick Elderly Patients with Hepatocellular Carcinoma in a Developing Country

Clinical experiences with microwave thermal ablation of lung malignancies

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