Complications of Pelvic Lymphadenectomy in 1,380 Patients Undergoing Radical Retropubic Prostatectomy Between 1993 and 2006

Musch, Michael; Klevecka, Virgilijus; Roggenbuck, Ulla; Kroepfl, Darko

doi:10.1016/j.juro.2007.10.072

Cited by 154 publications

(136 citation statements)

References 20 publications

Supporting

Mentioning

118

Contrasting

Unclassified

Order By: Relevance

“…With MI-PLND, 95 patients (95%) underwent extended and five patients (5%) underwent limited PLND: two obturator + hypogastric and three obturator-only. Operation time (skin-to-skin) was longer with MI-PLND (130 [70-240] vs 98 [59-200] min; P < 0.001), but there was less blood loss with MI-PLND (drop in hemoglobin on postoperative day 1: 1.1 ± 0.91 vs 1.7 ± 0.76 g/dL; P = 0.001) and hospital stay was shorter (3 [2][3][4][5][6][7][8][9][10][11][12][13][14] vs 6 [3-10] days; P < 0.001).…”

Section: Surgical Detailsmentioning

confidence: 99%

“…Contemporary PLND complication rates vary between 2-38%, with development of a symptomatic lymphocele being the main complication (0-11%). [8][9][10][11][12] Overall, (asymptomatic) lymphoceles have been reported in 18-61% of patients. [13][14][15] To our knowledge, only one study prospectively assessed the complication rate after laparoscopic staging PLND using a standardized classification.…”

Section: Introductionmentioning

confidence: 99%

“…[8][9][10][11][12] However, we included patients with "percutaneous lymphorrea >5 days postoperatively" as having a symptomatic lymphocele, which is not the case in most other reports. [8][9][10]12 Additionally, complication rates are known to be higher when data is gathered prospectively. 22 Although we found no significant difference between the type of surgery, in a series of 331 patients Danuser et al recently reported significantly less symptomatic lymphoceles after transperitoneal robot-assisted RP + extended PLND (1%) versus extraperitoneal open RP + extended PLND (5%; P = 0.06).…”

mentioning

confidence: 99%

See 2 more Smart Citations

Contemporary minimally‐invasive extended pelvic lymph node dissection for prostate cancer before curative radiotherapy: Prospective standardized analysis of complications

et al. 2014

View full text Add to dashboard Cite

Abbreviations & AcronymsObjectives: To prospectively assess contemporary complication rates of minimallyinvasive staging pelvic lymph node dissection before curative radiotherapy for prostate cancer using a standardized classification. Methods: A total of 100 prostate cancer patients underwent laparoscopic or robotassisted pelvic lymph node dissection (95% extended). Surgical outcomes were compared with those of 43 patients undergoing open pelvic lymph node dissection (33% extended).Complications were recorded prospectively during hospitalization and follow-up visits, and graded using Clavien-Dindo classification. Lymphocele size was measured on postoperative magnetic resonance imaging or computed tomography. Results: Of the complications recorded, 10% were grade 1, 3% were grade 2 and 6% were grade 3. No grade 4-5 complications occurred. Compared with open pelvic lymph node dissection, minimally-invasive pelvic lymph node dissection was associated with less blood loss (P = 0.001) and shorter hospital stay (median 3 vs 6 days; P < 0.001), but longer operation time (130 vs 98 min; P < 0.001). The complication rate was similar in both groups. For the entire cohort, overall and symptomatic lymphoceles were seen in 91 (64%) and 18 patients (13%), respectively. On multivariate logistic regression, minimally-invasive surgery was the only independent predictor for lymphocele development (odds ratio 3.99; P = 0.015). Conclusions: Minimally-invasive extended pelvic lymph node dissection before curative radiotherapy is associated with low morbidity. Asymptomatic lymphocele development rate is higher compared with open pelvic lymph node dissection.

show abstract

Section: Surgical Detailsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Contemporary minimally‐invasive extended pelvic lymph node dissection for prostate cancer before curative radiotherapy: Prospective standardized analysis of complications

et al. 2014

View full text Add to dashboard Cite

show abstract

“…4 Pelvic lymphoceles might require drainage to prevent possible clinical complications such as infection, pulmonary embolism and pressure on the neighboring organs. 5 The volume of fluid collection, localization, position, risk of infection, loculations and risk of relapse determine the treatment method. 6,7 Percutaneous aspiration with or without sclerotherapy, percutaneous drain insertion and open or laparoscopic drainage are among these methods.…”

Section: Introductionmentioning

confidence: 99%

Laparoscopic marsupialization of pelvic lymphoceles following radical prostatectomy

et al. 2018

View full text Add to dashboard Cite

Background: In this study, we evaluated our laparoscopic marsupialization experiences in patients who had radical prostatectomy due to prostate cancer and had lymphocele after the surgery.Methods: Between October 2011 and December 2013, radical prostatectomy and extended pelvic lymph node dissection were performed on 138 patients with prostate cancer diagnoses. Pelvic lymphocele was detected in 12 patients by ultrasonographic examination. Symptomatic patients to whom we applied drainage under ultrasonography and during whose follow-up lymphocele pouch was detected were hospitalized for laparoscopic marsupialization.Results: The 5 prostatectomy patients had a mean age of 67.9±15 (52-72) years. The time needed for lymphocele development was, on average, 63±12 (51-79) days and the mean lymphocele size was 8.6±1.2 (8-9) cm. Surgery was performed in the supine position with a transperitoneal laparoscopic approach. The average operating time was 80±20 (60-100) minutes. Patients had no collection in their ultrasonographic control examinations performed after 2 and 6 weeks and they have been followed-up for an average time of 20 months without problems.Conclusions: Although a limited number of patients were included in this study, the experience gained in urological laparoscopic operations indicates that laparoscopic marsupialization is an effective method that can be safely applied to treat lymphoceles requiring surgery.

show abstract

“…They can cause abdominal pain, deep vein thrombosis or lower urinary tract problems (1). Incidence, for example following open radical prostatectomy with pelvic lymph node dissection, varies in the literature between 3 and 14% (2). While treatment options encompass percutaneous aspiration with or without instillation of sclerosing agents and laparoscopic marsupialization, no standard is defined (1,3).…”

Section: Introductionmentioning

confidence: 99%

Conformal 3D planned radiotherapy for pelvic lymphoceles following surgery for urological cancer: A case study

Käsmann

Cegla

Rades

2016

Molecular and Clinical Oncology

View full text Add to dashboard Cite

Abstract. The aim of the present study was to evaluate the outcome and toxicity of 3D conformal radiotherapy (RT) for persistent lymphoceles following surgery for urological cancer. A total of 6 patients with bladder (n=1) and prostate cancer (n=5), with persistent lymphoceles following surgery for a primary tumor were treated with total doses of 10-12 Gy (1 Gy single dose) after computed tomography (CT) based 3D planning in order to suspend secretion. No acute or chronic toxicities were observed. In 5 patients, secretion of lymph fluid resolved after RT and in 1 patient RT had no effect. After a mean follow-up of 21 months (range, 5-47 months), no patient suffered from any symptoms concerning his former lymphoceles. This is the first analysis, to the best of our knowledge, to evaluate a homogenous patient collective of urological cancer patients with persistent lymphoceles after surgery for the initial tumor. RT to lymphoceles in urological cancer patient is effective, very well-tolerated and should be offered to patients with persistent secretion following drainage.

show abstract

Complications of Pelvic Lymphadenectomy in 1,380 Patients Undergoing Radical Retropubic Prostatectomy Between 1993 and 2006

Cited by 154 publications

References 20 publications

Contemporary minimally‐invasive extended pelvic lymph node dissection for prostate cancer before curative radiotherapy: Prospective standardized analysis of complications

Contemporary minimally‐invasive extended pelvic lymph node dissection for prostate cancer before curative radiotherapy: Prospective standardized analysis of complications

Laparoscopic marsupialization of pelvic lymphoceles following radical prostatectomy

Conformal 3D planned radiotherapy for pelvic lymphoceles following surgery for urological cancer: A case study

Contact Info

Product

Resources

About