Complications of Otitis Media Before Placement of Tympanostomy Tubes in Children

Kacmarynski, Deborah S. F.; Levine, Samuel C.; Pearson, Susan E.; Maisel, Robert H.

doi:10.1001/archotol.130.3.289

Cited by 15 publications

(10 citation statements)

References 8 publications

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“…1 Insertion of ventilation tubes (VTs) reduces the prevalence of MEE and produces a short-term benefit. 2 Long-term advantages of VT insertion in reducing the risk of subsequent linguistic, educational, and developmental impairments due to OME appear less uniform in different studies. [3][4][5][6] Five-year follow-up results after tympanostomy tube insertion showed that hearing in general was well preserved, but in one third of the ears the otological outcomes were abnormal, necessitating frequent follow-up visits or further treatment.…”

mentioning

confidence: 99%

A 14-Year Prospective Follow-up Study of Children Treated Early in Life With Tympanostomy Tubes: Part 2: Hearing Outcomes

Valtonen

Tuomilehto²,

Qvarnberg³

et al. 2005

Arch Otolaryngol Head Neck Surg

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mentioning

confidence: 99%

A 14-Year Prospective Follow-up Study of Children Treated Early in Life With Tympanostomy Tubes: Part 2: Hearing Outcomes

Valtonen

Tuomilehto²,

Qvarnberg³

et al. 2005

Arch Otolaryngol Head Neck Surg

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“…However, studies of GA for neuroimaging23, some otorhinolaryngology procedures (e.g. adenotonsillectomy for obstructive sleep apnea associated with learning difficulty49,58 or myringotomy and grommet insertion associated with speech/language delay59), pyloromyotomy associated with significant hyperbilirubinemia24 or nutritional inadequacy48, gastroschisis34, craniosyntosis18 and cancer surgery60 may be similarly compromised.…”

Section: Choice Of Interventionmentioning

confidence: 99%

Assessing Long-term Neurodevelopmental Outcome Following General Anesthesia in Early Childhood: Challenges and Opportunities

Walkden

Pickering

Gill

2019

Anesthesia &Amp; Analgesia

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Neurodegeneration has been reported in young animals after exposure to all the commonly used general anesthetics (GA). The brain may be particularly vulnerable to anesthetic toxicity during peak synaptogenesis (in gestation and infancy). Human studies of long-term neurodevelopmental outcome following GA in early childhood report contradictory findings. This review assesses the strengths and deficiencies in human research methodologies to inform future studies. We identified 76 studies, published between 1990 and 2017, of long-term neurodevelopmental outcome following early childhood or in utero GA exposure: 49 retrospective, 9 ambi-directional, 17 prospective cohort studies and one randomized controlled trial (RCT). Forty-nine studies were explicitly concerned with anesthetic-induced neurotoxicity (AIN). Full texts were appraised for methodological challenges and possible solutions. Major challenges identified included: delineating effects of anesthesia from surgery; defining the timing and duration of exposure; selection of a surgical cohort and intervention; addressing multiple confounding life course factors; detecting modest neurotoxic effects with small sample sizes (median 131 children, IQR: 50-372); selection of sensitive neurodevelopmental outcomes at appropriate ages for different developmental domains; insufficient length of follow-up (median age: 6 years, IQR: 2-12) and sample attrition. We discuss potential solutions to these challenges. Further adequately powered, multi-center, prospective RCT of AIN in children are required. However, we believe that the inherent methodological challenges of studying AIN necessitate the parallel use of well-designed observational cohort studies.

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“…There are also potential sequelae to AOM that add to the burden of OM itself, including hearing loss, often obvious in the short-term, and impaired speech and psychosocial development ( Fig. 1) [13,19,20].…”

Section: Global Burden Of Ommentioning

confidence: 99%

Challenges in reducing the burden of otitis media disease: An ENT perspective on improving management and prospects for prevention

Grevers¹

2010

International Journal of Pediatric Otorhinolaryngology

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Acute otitis media (AOM) is a major public health concern. This frequent disease of childhood is a leading cause of physician visits, a major component of paediatric healthcare burden, and a key contributor to antibiotic resistance. An international expert group comprising mainly ear, nose, and throat physicians met in June 2008 to discuss the optimal management of AOM, particularly with regards to unmet needs in diagnosis and management. Current guidelines do not help identify which patients are most at risk for severe or complicated AOM. Diagnosis of AOM is also complicated by a lack of correlation between clinical signs and symptoms and responsible pathogens. Consequently, treatment of AOM is not always appropriate, and the long-term overuse of antibiotics in AOM reduces the effectiveness of treatment and places children at risk for drug-resistant infections. There is a need for educational and research initiatives to improve diagnostic accuracy and management of AOM. Because there is currently no ideal treatment, vaccination is an attractive additional approach for managing AOM and reducing its burden.

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Complications of Otitis Media Before Placement of Tympanostomy Tubes in Children

Cited by 15 publications

References 8 publications

A 14-Year Prospective Follow-up Study of Children Treated Early in Life With Tympanostomy Tubes: Part 2: Hearing Outcomes

A 14-Year Prospective Follow-up Study of Children Treated Early in Life With Tympanostomy Tubes: Part 2: Hearing Outcomes

Assessing Long-term Neurodevelopmental Outcome Following General Anesthesia in Early Childhood: Challenges and Opportunities

Challenges in reducing the burden of otitis media disease: An ENT perspective on improving management and prospects for prevention

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